Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review

J Karami, S Aslani, A Jamshidi, M Garshasbi… - Gene, 2019 - Elsevier
Three important factors, including genetics, environment factors and autoimmunity play a
role in the pathogenesis of rheumatoid arthritis (RA). The heritability of RA has been …

Genetics of rheumatoid arthritis—a comprehensive review

J Kurkó, T Besenyei, J Laki, TT Glant, K Mikecz… - Clinical reviews in …, 2013 - Springer
The “Bermuda triangle” of genetics, environment and autoimmunity is involved in the
pathogenesis of rheumatoid arthritis (RA). Various aspects of genetic contribution to the …

Anti-CCP antibodies: the past, the present and the future

WJ Van Venrooij, JJBC Van Beers… - Nature Reviews …, 2011 - nature.com
Rheumatoid arthritis (RA) is an autoimmune disease characterized by autoantibodies
against citrullinated antigens. The importance of citrulline for the epitopes bound by these …

[HTML][HTML] Different risk factors between interstitial lung disease and airway disease in rheumatoid arthritis

S Mori, Y Koga, M Sugimoto - Respiratory medicine, 2012 - Elsevier
OBJECTIVE: To identify clinical and genetic risk factors for interstitial lung disease (ILD) or
airway disease (AD) in patients with rheumatoid arthritis (RA) and to evaluate differences …

An overview on the genetic of rheumatoid arthritis: a never-ending story

C Perricone, F Ceccarelli, G Valesini - Autoimmunity reviews, 2011 - Elsevier
Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory, multi-factorial disease
sustained by environmental and genetic factors. These seem to be necessary but not …

The genetic pathogenesis, diagnosis and therapeutic insight of rheumatoid arthritis

M Zamanpoor - Clinical genetics, 2019 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease that causes chronic
inflammation of the joints. RA is a heterogeneous disorder caused by an abnormal …

[HTML][HTML] Rheumatoid arthritis susceptibility genes: An overview

I Korczowska - World journal of orthopedics, 2014 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disease sustained by
genetic factors. Various aspects of the genetic contribution to the pathogenetics and …

The relevance of citrullinated vimentin in the production of antibodies against citrullinated proteins and the pathogenesis of rheumatoid arthritis

K Van Steendam, K Tilleman, D Deforce - Rheumatology, 2011 - academic.oup.com
Antibodies against citrullinated proteins (ACPAs) are highly specific for RA. Since the
discovery of these antibodies, several of studies that focused on the presence and identity of …

HLA shared epitope and ACPA: just a marker or an active player?

F Pratesi, EP Teixeira, J Sidney, L Michou… - Autoimmunity …, 2013 - Elsevier
Autoantibody production is genetically controlled and anti-citrullinated protein/peptide
antibodies (ACPA) are not an exception to the rule. ACPA are highly specific markers of …

Comparison of serological biomarkers in rheumatoid arthritis and their combination to improve diagnostic performance

L Martinez-Prat, MJ Nissen, C Lamacchia… - Frontiers in …, 2018 - frontiersin.org
Introduction The diagnosis of rheumatoid arthritis (RA) is based on a combined approach
that includes serological markers such as rheumatoid factor (RF) and anti-citrullinated …