TFOS DEWS II diagnostic methodology report

JS Wolffsohn, R Arita, R Chalmers, A Djalilian… - The ocular …, 2017 - Elsevier
The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

BCLA CLEAR-Anatomy and physiology of the anterior eye

LE Downie, S Bandlitz, JPG Bergmanson… - Contact Lens and …, 2021 - Elsevier
A key element of contact lens practice involves clinical evaluation of anterior eye health,
including the cornea and limbus, conjunctiva and sclera, eyelids and eyelashes, lacrimal …

Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

M Wu, LJ Hill, LE Downie, HR Chinnery - Progress in Retinal and Eye …, 2022 - Elsevier
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

A randomized, double-masked, placebo-controlled clinical trial of two forms of omega-3 supplements for treating dry eye disease

LA Deinema, AJ Vingrys, CY Wong, DC Jackson… - Ophthalmology, 2017 - Elsevier
Purpose To assess the efficacy of 2 forms of oral long-chain omega-3 (ω-3) essential fatty
acid (EFA) supplements, phospholipid (krill oil) and triacylglyceride (fish oil), for treating dry …

Clinical impact of inflammation in dry eye disease: proceedings of the ODISSEY group meeting

C Baudouin, M Irkeç, EM Messmer… - Acta …, 2018 - Wiley Online Library
Dry eye disease (DED) is a common, multifactorial ocular condition with major impact on
vision and quality of life. It is now well recognized that the pathophysiology of chronic DED …

Ocular surface diseases induced by dupilumab in severe atopic dermatitis

A Maudinet, S Law-Koune, C Duretz, A Lasek… - Ophthalmology and …, 2019 - Springer
We report 10 cases of conjunctivitis in atopic dermatitis (AD) patients treated with dupilumab
from November 2017 to November 2018 in our institution, who were referred to the …

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease

LE Downie, SM Ng, KB Lindsley… - Cochrane Database of …, 2019 - cochranelibrary.com
Background Polyunsaturated fatty acid (PUFA) supplements, involving omega‐3 and/or
omega‐6 components, have been proposed as a therapy for dry eye. Omega‐3 PUFAs exist …

Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation

A Mahajan, L Hasíková, U Hampel, A Grüneboom… - The Ocular Surface, 2021 - Elsevier
Abstract Purpose Obstructive Meibomian gland dysfunction (MGD) is one of the leading
causes of evaporative dry eye disease. Meibomian glands at the eyelid secrete lipids that …

TFOS DEWS II clinical trial design report

GD Novack, P Asbell, S Barabino, MVW Bergamini… - The ocular …, 2017 - Elsevier
The development of novel therapies for Dry Eye Disease (DED) is formidable, and relatively
few treatments evaluated have been approved for marketing. In this report, the …

Tear biomarkers in dry eye disease: Progress in the last decade

NR Kumar, M Praveen, R Narasimhan… - Indian journal of …, 2023 - journals.lww.com
Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …