How I prevent GVHD in high-risk patients: posttransplant cyclophosphamide and beyond

J Rimando, SR McCurdy, L Luznik - Blood, 2023 - ashpublications.org
Advances in conditioning, graft-versus-host disease (GVHD) prophylaxis and antimicrobial
prophylaxis have improved the safety of allogeneic hematopoietic cell transplantation (HCT) …

The development of post-transplant cyclophosphamide: Half a century of translational team science

PV O'Donnell, RJ Jones - Blood reviews, 2023 - Elsevier
Close HLA matching of donors and recipients has been the dogma for successful allogeneic
blood or marrow transplantation (alloBMT), to limit the complications of graft-versus-host …

PTCy, abatacept, and a short course of tacrolimus for GVHD prevention after haploidentical transplantation

AS Al-Homsi, F Cirrone, S Wo, K Cole… - Blood …, 2023 - ashpublications.org
Reducing the incidence of graft-versus-host disease (GVHD) after haploidentical
hematopoietic stem cell transplantation (HSCT) is warranted. Posttransplant …

Recipient clonal hematopoiesis in allogeneic bone marrow transplantation for lymphoid malignancies

PH Imus, S Pasca, HL Tsai, YM Aljawai… - Blood …, 2024 - ashpublications.org
Allogeneic blood and marrow transplantation (alloBMT) is increasingly being used in older
patients with blood cancer. Aging is associated with an increasing incidence of clonal …

Peripheral blood haploidentical hematopoietic cell transplantation for patients aged 70 years and over with acute myeloid leukemia or high-risk myelodysplastic …

S Harbi, L Brac de la Perriere, B Bouchacourt… - Bone Marrow …, 2024 - nature.com
Haploidentical stem cell transplantation (Haplo-SCT) using non-myeloablative conditioning
regimen (NMAC) has extended the feasibility of allogeneic transplantation, notably in older …

Systematic overview of HLA-matched allogeneic hematopoietic cell transplantation with post-transplantation cyclophosphamide

H Nakamae - International Journal of Hematology, 2022 - Springer
The successful application of post-transplantation cyclophosphamide (PTCy) as graft-versus-
host disease (GVHD) prophylaxis in HLA-haploidentical allogeneic hematopoietic cell …

Post-transplantation cyclophosphamide-based graft-versus-host disease prophylaxis with nonmyeloablative conditioning for blood or marrow transplantation for …

T Jain, HL Tsai, AE DeZern, LP Gondek… - … and cellular therapy, 2022 - Elsevier
We describe outcomes after post-transplantation cyclophosphamide and nonmyeloablative
conditioning-based allogeneic blood or marrow transplantation for myelofibrosis using …

[HTML][HTML] Nonmyeloablative, HLA-mismatched unrelated peripheral blood transplantation with high-dose post-transplantation cyclophosphamide

KC Rappazzo, M Zahurak, M Bettinotti, SA Ali… - … and cellular therapy, 2021 - Elsevier
High-dose post-transplantation cyclophosphamide (PTCy) is an effective platform for
prevention of severe graft-versus-host disease (GVHD) after allogeneic bone marrow (BM) …

[HTML][HTML] Current challenges in conditioning regimens for MDS transplantation

AB Notarantonio, M Robin, M D'Aveni - Blood Reviews, 2024 - Elsevier
Myelodysplastic syndrome (MDS) is a very heterogeneous clonal disorder. Patients with
“higher-risk” MDS, defined by specific recurrent genetic abnormalities, have a poor …

Feasibility and safety of the discontinuation of systemic immunosuppressive treatment after single-unit cord blood transplantation in adults

T Konuma, M Monna-Oiwa, S Kato, M Isobe… - Bone Marrow …, 2024 - nature.com
We retrospectively evaluated the incidence, factors, and clinical outcomes of the
discontinuation of immunosuppressive treatment (IST) after single-unit unrelated cord blood …