The RAF/MEK/ERK signaling pathway regulates diverse cellular processes as exemplified
by cell proliferation, differentiation, motility, and survival. Activation of ERK1/2 generally …

Arsenic poisoning is a global health problem. Chronic exposure to arsenic has been
associated with the development of a wide range of diseases and health problems in …

The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …

Endoplasmic reticulum stress (ER stress) is triggered due to a loss of homeostasis in the ER,
resulting in accumulation of misfolded proteins in the ER lumen. ER stress activates a series …

As a carrier, nanoplastics (NPs) can adsorb other toxic substances and thus modify their
biological toxicity. Numerous studies have investigated the neurotoxic of high concentrations …

Arsenic is a metalloid found in groundwater as a byproduct of soil/rock erosion and industrial
and agricultural processes. This xenobiotic elicits its toxicity through different mechanisms …

Fluoride is an element with toxic properties and has been proven to have some adverse
effects on many soft tissues, including brain tissue. This study aims to evaluate the protective …

Arsenic is a toxic metalloid present ubiquitously on earth. Since the last decade, it has
gained considerable attention due to its severe neurotoxic effects. Arsenic can cross the …

Arsenic is the leading toxicant of hazardous environmental chemicals, which is linked with
neurotoxicity including cognitive dysfunction, neurodevelopmental alterations and …

For the past decade, there has been an increased concern about the health risks from
arsenic (As) exposure, because of its neurotoxic effects on the developing brain. The exact …