Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …

Unlike neurologic conditions, such as brain tumors, dementia, and stroke, the neural
mechanisms for all psychiatric disorders remain unclear. A large body of research obtained …

Objective: The authors sought to describe the emergent course of bipolar disorder in
offspring of affected parents subgrouped by parental response to lithium prophylaxis …

After decades of research, the mechanism of action of lithium in preventing recurrences of
bipolar disorder remains only partially understood. Lithium research is complicated by the …

Bipolar disorders (BDs) are among the leading causes of morbidity and disability. Objective
biological markers, such as those based on brain imaging, could aid in clinical management …

MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …

Objective The study examined gray matter volume across psychosis diagnoses organized
by dimensional and DSM-IV categories from the Bipolar-Schizophrenia Network on …

Background The greater presence of neurodevelopmental antecedants may differentiate
schizophrenia from bipolar disorders (BD). Machine learning/pattern recognition allows us to …

Background Bipolar disorder (BD) is characterized by a dysregulation of affect and impaired
integration of emotion with cognition. These traits are also expressed in probands at high …

The phenomenology and underlying pathophysiology of bipolar disorder (BD) are
heterogeneous. The identification of putative endophenotypes for BD can aid in the …