2-Azabicyclo [2.2. 1] hept-5-en-3-one: chemical profile of a versatile synthetic building block and its impact on the development of therapeutics

R Singh, R Vince - Chemical Reviews, 2012 - ACS Publications
Replacement of the furanosyl oxygen with a methylene unit in the ribose sugar in
nucleosides 1 and nucleotides 2 prompted the rise of a new nucleoside class with very …

Formation of m-and p-coumaric acids by enzymatic deamination of the corresponding isomers of tyrosine

AC Neish - Phytochemistry, 1961 - Elsevier
An enzyme was found which catalyzes the deamination of l-tyrosine, giving equimolar
amounts of trans-p-coumaric acid and ammonia as the products. This enzyme (tyrase) was …

Optimized Synthesis of l-m-Tyrosine Suitable for Chemical Scale-Up

CE Humphrey, M Furegati, K Laumen… - … Process Research & …, 2007 - ACS Publications
This paper demonstrates how lm-tyrosine 1 can be synthesized on larger-scale via enzyme-
catalyzed kinetic resolution of N-acyl m-tyrosine methyl ester 4. N-Acyl m-tyrosine methyl …

Solvent-Induced Reversed Stereoselectivity in Reciprocal Resolutions of Mandelic Acid and erythro-2-Amino-1,2-diphenylethanol

H Shitara, T Shintani, K Kodama… - The Journal of Organic …, 2013 - ACS Publications
Solvent-induced chirality switching in reciprocal optical resolution between mandelic acid
(1) and erythro-2-amino-1, 2-diphenylethanol (2) has been demonstrated. The …

Properties of the ammonia-lyases deaminating phenylalanine and related compounds in Triticum aestivum and Pteridium aquilinum

MR Young, AC Neish - Phytochemistry, 1966 - Elsevier
Wheat shoot acetone powders contain ammonia-lyases which catalyse the conversion of a
number of ring-substituted phenylalanines to the corresponding cinnamic acids. The …

Biogenetic studies on volucrisporin

G Read, LC Vining, RH Haskins - Canadian Journal of …, 1962 - cdnsciencepub.com
In experiments with C14-labelled compounds, shikimic acid, phenylalanine, phenyllactic
acid, and metatyrosine were found to be precursors of the terphenylquinone pigment …

Solid-phase synthesis of α-amino acids by radical addition to adehydroalanine derivative

AM Yim, Y Vidal, P Viallefont, J Martinez - Tetrahedron letters, 1999 - Elsevier
The first synthesis of N-acetyl-α-amino acids by radical addition on solid support to
commercialy available 2-acetamidoacrylic acid using the mercury method is described The …

Preparation of m-Hydroxyphenyl-L- and D-Lactic Acids and Other Compounds Related to m-Tyrosine1

KNF SHAW, MD ARMSTRONG… - The Journal of Organic …, 1956 - ACS Publications
2-Methyl-4-(3'-acetoxybenzal)-5-oxazolone was hydrolyzed to yield m-hydroxyphenylpyruvic
acid, which was reduced to m-hydroxyphenyllactic acid. m-Hydroxyphenyllactic acid ivas …

Purification and some properties of L-tyrosine carboxy-lyase from barley roots

K Hosoi - Plant and cell physiology, 1974 - academic.oup.com
L-Tyrosine carboxy-lyase (EC 4. 1. 1. 25) was extracted from the roots of barley seedlings
and purified approximately 25 fold. Optimum pH for the enzyme activity was found to be 7.3 …

Amino acid oxidase‐catalysed resolution and Pictet–Spengler reaction towards chiral and rigid unnatural amino acids

P Benz, R Wohlgemuth - Journal of Chemical Technology & …, 2007 - Wiley Online Library
BACKGROUND: The biosynthesis of structurally complex isoquinoline alkaloids and other
natural products occurs via aromatic amino acids such as tyrosine, and chiral and rigid …