Interplay between the immune and endocrine systems in the lung: implications for TB susceptibility

T Webber, K Ronacher, M Conradie-Smit… - Frontiers in …, 2022 - frontiersin.org
The role of the endocrine system on the immune response, especially in the lung, remains
poorly understood. Hormones play a crucial role in the development, homeostasis …

Immunopathology in human pulmonary tuberculosis: Inflammatory changes in the plasma milieu and impaired host immune cell functions

HS Ahor, M Vivekanandan, JDD Harelimana… - …, 2024 - Wiley Online Library
Host immune response is key for protection in tuberculosis, but the causative agent,
Mycobacterium (M.) tuberculosis, manages to survive despite immune surveillance. Key …

Estradiol inhibits autophagy of Mycobacterium tuberculosis‑infected 16HBE cells and controls the proliferation of intracellular Mycobacterium tuberculosis

Y Gan, Q Hu, A Li, L Gu, S Guo - Molecular Medicine …, 2022 - spandidos-publications.com
Tracheobronchial tuberculosis (TBTB) is most common in young, middle‑aged females.
Despite adequate anti‑tuberculosis therapy,> 90% of patients develop tracheobronchial …

Alteration of endocrine hormones and antibody responses in different spectrum of tuberculosis disease

Y Tsegaye, W Admassu, A Edao, S Kinde… - Frontiers in …, 2022 - frontiersin.org
Effective control of Mycobacterium tuberculosis (Mtb) infection is mediated by multifaceted
factors that involve both the endocrine and immune system. Profiling hormones and …

Evidence for a more disrupted immune-endocrine relation and cortisol immunologic influences in the context of tuberculosis and type 2 diabetes comorbidity

RDV Fernández, A Díaz, B Bongiovanni… - Frontiers in …, 2020 - frontiersin.org
Pulmonary tuberculosis (PTB), caused by Mycobacterium tuberculosis (Mtb), is a major
health problem worldwide, further aggravated by the convergence of type 2 diabetes …

16α-Bromoepiandrosterone as a new candidate for experimental diabetes–tuberculosis co-morbidity treatment

MO López-Torres, B Marquina-Castillo… - Clinical & …, 2021 - academic.oup.com
Tuberculosis (TB) is the leading cause of death from a single bacterial infectious agent and
is one of the most relevant issues of public health. Another pandemic disease is type II …

Association between IL-15 and insulin plasmatic concentrations in patients with pulmonary tuberculosis and type 2 diabetes

R Sanchez-Jimenez, E Ceron, D Bernal-Alcantara… - Tuberculosis, 2018 - Elsevier
IL-15 is part of the immune response in pulmonary tuberculosis (PTB) but amazingly, it may
also induce physiological effects similar to those of insulin. We evaluated the IL-15 and …

Local regulation of adrenal steroidogenesis: subtle in vitro effects of IL-1β on the human cell line NCI-H295R steroid production along with changes in microRNA …

N Santucci, R Stampone… - …, 2021 - karger.com
Abstract Introduction: IL-1β, a cytokine from the innate immune response, is well known for
its proinflammatory effects and stimulating activity on the hypothalamus-pituitary-adrenal …

16a-Bromoepiandrosterone as a new candidate for diabetes-tuberculosis comorbidity treatment

MOL Torres, B Marquina, O Ramos-Espinosa… - Authorea …, 2020 - techrxiv.org
Being the leading cause of mortality by a single infectious agent, tuberculosis (TB) continues
as one of the most relevant issues of public health. Another pandemic disease is type 2 …

[PDF][PDF] COLLEGE OF HEALTH SCIENCES DEPARTMENT OF MEDICAL LABORATORY SCIENCES

Y Tsegaye - 2019 - academia.edu
Background: Hormones often act as immunomodulators. Immune and endocrine interaction
during infectious diseases may determine the failure or success of the immune response …