The technological landscape and applications of single-cell multi-omics
Single-cell multi-omics technologies and methods characterize cell states and activities by
simultaneously integrating various single-modality omics methods that profile the …
simultaneously integrating various single-modality omics methods that profile the …
[HTML][HTML] Multi-omics approaches in cancer research with applications in tumor subtyping, prognosis, and diagnosis
O Menyhárt, B Győrffy - Computational and structural biotechnology journal, 2021 - Elsevier
While cost-effective high-throughput technologies provide an increasing amount of data, the
analyses of single layers of data seldom provide causal relations. Multi-omics data …
analyses of single layers of data seldom provide causal relations. Multi-omics data …
Onco‐multi‐OMICS approach: a new frontier in cancer research
The acquisition of cancer hallmarks requires molecular alterations at multiple levels
including genome, epigenome, transcriptome, proteome, and metabolome. In the past …
including genome, epigenome, transcriptome, proteome, and metabolome. In the past …
Understanding the HPV integration and its progression to cervical cancer
MA Oyervides-Muñoz, AA Pérez-Maya… - Infection, Genetics and …, 2018 - Elsevier
Cervical cancer is one of the main causes of female cancer death worldwide, and human
papilloma virus (HPV) its causal agent. To investigate viral oncogenesis several studies …
papilloma virus (HPV) its causal agent. To investigate viral oncogenesis several studies …
The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications
SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
Artificial intelligence to decode cancer mechanism: beyond patient stratification for precision oncology
The multitude of multi-omics data generated cost-effectively using advanced high-
throughput technologies has imposed challenging domain for research in Artificial …
throughput technologies has imposed challenging domain for research in Artificial …
Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes
Cervical cancer is the most common cancer affecting sub-Saharan African women and is
prevalent among HIV-positive (HIV+) individuals. No comprehensive profiling of cancer …
prevalent among HIV-positive (HIV+) individuals. No comprehensive profiling of cancer …
Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers
Although promoter-associated CpG islands have been established as targets of DNA
methylation changes in cancer, previous studies suggest that epigenetic dysregulation …
methylation changes in cancer, previous studies suggest that epigenetic dysregulation …
Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification
Background There is significant interest in treatment de-escalation for human papillomavirus-
associated (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) patients given the …
associated (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) patients given the …
Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers
DE Symer, K Akagi, HM Geiger, Y Song, G Li… - Genome …, 2022 - genome.cshlp.org
Human papillomavirus (HPV) causes 5% of all cancers and frequently integrates into host
chromosomes. The HPV oncoproteins E6 and E7 are necessary but insufficient for cancer …
chromosomes. The HPV oncoproteins E6 and E7 are necessary but insufficient for cancer …