[HTML][HTML] Polychemotherapy with curcumin and doxorubicin via biological nanoplatforms: enhancing antitumor activity

M Ashrafizadeh, A Zarrabi, F Hashemi, A Zabolian… - Pharmaceutics, 2020 - mdpi.com
Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …

A Systematic Review of the Potential Chemoprotective Effects of Resveratrol on Doxorubicin‐Induced Cardiotoxicity: Focus on the Antioxidant, Antiapoptotic, and Anti …

LF Hu, HR Lan, XM Li, KT Jin - Oxidative medicine and cellular …, 2021 - Wiley Online Library
Purpose. Although doxorubicin chemotherapeutic drug is commonly used to treat various
solid and hematological tumors, its clinical use is restricted because of its adverse effects on …

Curcumin ameliorates doxorubicin-induced cardiotoxicity and hepatotoxicity via suppressing oxidative stress and modulating iNOS, NF-κB, and TNF-α in rats

G Ibrahim Fouad, KA Ahmed - Cardiovascular toxicology, 2022 - Springer
Doxorubicin (DOX) is one of the widely used anti-tumor drugs. However, DOX-induced
cardiotoxicity (DIC) and hepatotoxicity (DIH) are among the side effects that limited its …

Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway

AAM Sallam, SF Darwish, WA El-Dakroury… - Pharmaceutical …, 2021 - Springer
Aims Gastric ulcer is a continuous worldwide threat that inquires protective agents.
Olmesartan (OLM) has potent anti-oxidant and anti-inflammatory characters, yet having …

l-Carnitine and vitamin E ameliorate cardiotoxicity induced by tilmicosin in rats

M Aboubakr, F Elsayd, A Soliman, SE Fadl… - … Science and Pollution …, 2020 - Springer
The present study aimed to investigate the possible mitigating effect of l-carnitine (LC)
and/or α-tocopherol (Vit. E) administration against tilmicosin (TIL)-induced cardiotoxicity in …

The nutraceutical value of carnitine and its use in dietary supplements

A Durazzo, M Lucarini, A Nazhand, SB Souto, AM Silva… - Molecules, 2020 - mdpi.com
Carnitine can be considered a conditionally essential nutrient for its importance in human
physiology. This paper provides an updated picture of the main features of carnitine …

Dexrazoxane Protects Cardiomyocyte from Doxorubicin‐Induced Apoptosis by Modulating miR‐17‐5p

X Yu, Y Ruan, T Shen, Q Qiu, M Yan… - BioMed research …, 2020 - Wiley Online Library
The usage of doxorubicin is hampered by its life‐threatening cardiotoxicity in clinical
practice. Dexrazoxane is the only cardioprotective medicine approved by the FDA for …

Anethole alleviates Doxorubicin-induced cardiac and renal toxicities: Insights from network pharmacology and animal studies

MA Al-Ali, NS Younis, B Aldhubiab, AS Alatawi… - Chemico-Biological …, 2024 - Elsevier
Doxorubicin (Dox) is widely used as a chemotherapy drug, while anethole (AN) is primarily
known as the main aromatic component in various plant species. This research focused on …

The role of nutrition in primary and secondary prevention of cardiovascular damage in childhood cancer survivors

F Guida, R Masetti, L Andreozzi, D Zama, M Fabi… - Nutrients, 2022 - mdpi.com
Innovative therapeutic strategies in childhood cancer led to a significant reduction in cancer-
related mortality. Cancer survivors are a growing fragile population, at risk of long-term side …

Protective effect of Eprosartan against ischemic acute renal injury: Acting on NF-κB, caspase 3, and Sirtuin 1

B Lotfi, Y Bagheri, A Abdollahpour, E Ahmadian… - International …, 2023 - Elsevier
Kidney ischemia/reperfusion (I/R) injury is a leading cause of acute kidney injury (AKI)
occurring frequently under major surgeries and sepsis. This study aimed to evaluate the …