Pathogenesis of cholangiocarcinoma
PM Rodrigues, P Olaizola, NA Paiva… - Annual Review of …, 2021 - annualreviews.org
Cholangiocarcinoma (CCA) encompasses a group of malignancies that can arise at any
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …
International Union of Basic and Clinical Pharmacology. LXXXIII: classification of prostanoid receptors, updating 15 years of progress
DF Woodward, RL Jones, S Narumiya - Pharmacological reviews, 2011 - ASPET
It is now more than 15 years since the molecular structures of the major prostanoid receptors
were elucidated. Since then, substantial progress has been achieved with respect to …
were elucidated. Since then, substantial progress has been achieved with respect to …
Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma
Background & Aims Little is known about the metabolic regulation of cancer stem cells
(CSCs) in cholangiocarcinoma (CCA). We analyzed whether mitochondrial-dependent …
(CSCs) in cholangiocarcinoma (CCA). We analyzed whether mitochondrial-dependent …
[PDF][PDF] Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment
B Blechacz, GJ Gores - Hepatology, 2008 - Wiley Online Library
Cholangiocarcinoma (CCA) is an epithelial can-cer originating from the bile ducts with
features of cholangiocyte differentiation. 1 CCA is the second most common primary hepatic …
features of cholangiocyte differentiation. 1 CCA is the second most common primary hepatic …
Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle
R Ramasamy, H Fazekasova, EWF Lam, I Soeiro… - …, 2007 - journals.lww.com
Background. Mesenchymal stem cells (MSCs) play a crucial role in hematopoietic
development and have been shown to exert a powerful immunosuppressive effect. In this …
development and have been shown to exert a powerful immunosuppressive effect. In this …
Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics
CM Ulrich, J Bigler, JD Potter - Nature Reviews Cancer, 2006 - nature.com
Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) show indisputable
promise as chemopreventive agents. Possible targets include cancers of the colon, stomach …
promise as chemopreventive agents. Possible targets include cancers of the colon, stomach …
Epidemiology and risk factors of cholangiocarcinoma
MM Kirstein, A Vogel - Visceral medicine, 2016 - karger.com
Background: Cholangiocarcinoma (CCA) is the second most common primary liver cancer,
being characterized by its late diagnosis and fatal outcome. Recent epidemiological reports …
being characterized by its late diagnosis and fatal outcome. Recent epidemiological reports …
COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells
R Ramer, K Heinemann, J Merkord, H Rohde… - Molecular cancer …, 2013 - AACR
The antitumorigenic mechanism of cannabidiol is still controversial. This study investigates
the role of COX-2 and PPAR-γ in cannabidiol's proapoptotic and tumor-regressive action. In …
the role of COX-2 and PPAR-γ in cannabidiol's proapoptotic and tumor-regressive action. In …
Prostaglandin E2 receptor distribution and function in the gastrointestinal tract
I Dey, M Lejeune, K Chadee - British journal of pharmacology, 2006 - Wiley Online Library
Prostaglandin E2 (PGE2) is one of the most important biologically active prostanoids found
throughout the gastrointestinal tract. Despite the fact that PGE2 regulates many …
throughout the gastrointestinal tract. Despite the fact that PGE2 regulates many …
Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages
Background & Aims A therapeutically challenging subset of cells, termed cancer stem cells
(CSCs) are responsible for cholangiocarcinoma (CCA) clinical severity. Presence of tumor …
(CSCs) are responsible for cholangiocarcinoma (CCA) clinical severity. Presence of tumor …