Role of oxidative stress in male infertility: an updated review

AT Alahmar - Journal of human reproductive sciences, 2019 - journals.lww.com
Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations

SC Esteves, A Zini, RM Coward, DP Evenson… - Andrologia, 2021 - Wiley Online Library
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Contribution of semen to early embryo development: fertilization and beyond

M Vallet-Buisan, R Mecca, C Jones… - Human …, 2023 - academic.oup.com
BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …

[HTML][HTML] Sperm DNA fragmentation: a new guideline for clinicians

A Agarwal, A Majzoub, S Baskaran… - The world journal of …, 2020 - ncbi.nlm.nih.gov
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Impact of advanced paternal age on fertility and risks of genetic disorders in offspring

A Kaltsas, E Moustakli, A Zikopoulos, I Georgiou… - Genes, 2023 - mdpi.com
The average age of fathers at first pregnancy has risen significantly over the last decade
owing to various variables, including a longer life expectancy, more access to contraception …

A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome

L Simon, A Zini, A Dyachenko, A Ciampi… - Asian journal of …, 2017 - journals.lww.com
Sperm DNA damage is prevalent among infertile men and is known to influence natural
reproduction. However, the impact of sperm DNA damage on assisted reproduction …

Reactive oxygen species impact on sperm DNA and its role in male infertility

AD Bui, R Sharma, R Henkel, A Agarwal - Andrologia, 2018 - Wiley Online Library
Reactive oxygen species (ROS) have been extensively studied as a cause of male infertility.
Excessive levels of ROS coupled with a deficiency in antioxidants can lead to oxidative …

Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring

R Sharma, A Agarwal, VK Rohra, M Assidi… - Reproductive Biology …, 2015 - Springer
Over the last decade, there has been a significant increase in average paternal age when
the first child is conceived, either due to increased life expectancy, widespread use of …

Antioxidants for male subfertility

W de Ligny, RM Smits… - Cochrane database …, 2022 - cochranelibrary.com
Background The inability to have children affects 10% to 15% of couples worldwide. A male
factor is estimated to account for up to half of the infertility cases with between 25% to 87% of …

The semen microbiome and its impact on sperm function and male fertility: a systematic review and meta‐analysis

L Farahani, T Tharakan, T Yap, JW Ramsay… - …, 2021 - Wiley Online Library
Background Male factor is attributable in up to 50% of cases of infertility. In vitro studies
demonstrate that bacteria can negatively impact sperm function. The use of next‐generation …