Complex roles for sulfation in the toxicities of polychlorinated biphenyls
MW Duffel, HJ Lehmler - Critical reviews in toxicology, 2024 - Taylor & Francis
Polychlorinated biphenyls (PCBs) are persistent organic toxicants derived from legacy
pollution sources and their formation as inadvertent byproducts of some current …
pollution sources and their formation as inadvertent byproducts of some current …
Epigenetics in drug disposition & drug therapy: symposium report of the 24th North American meeting of the International Society for the Study of Xenobiotics (ISSX)
BJ Maldonato, AG Vergara, J Yadav… - Drug metabolism …, 2022 - Taylor & Francis
Abstract The 24th North American International Society for the Study of Xenobiotics (ISSX)
meeting, held virtually from September 13 to 17, 2021, embraced the theme of “Broadening …
meeting, held virtually from September 13 to 17, 2021, embraced the theme of “Broadening …
[HTML][HTML] Age-dependent energy metabolism and transcriptome changes in urine-derived stem cells
The global population over 60 years old is projected to reach 1.5 billion by 2050.
Understanding age-related disorders and gender-specificities is crucial for a healthy aging …
Understanding age-related disorders and gender-specificities is crucial for a healthy aging …
Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model
Hepatic xenobiotic metabolism and transport decline with age, while intact xenobiotic
metabolism is associated with longevity. However, few studies have examined the genome …
metabolism is associated with longevity. However, few studies have examined the genome …
Epigenetic regulation of drug metabolism in aging: utilizing epigenetics to optimize geriatric pharmacotherapy
S Abudahab, PW Slattum, ET Price… - Pharmacogenomics, 2024 - Taylor & Francis
We explore the relationship between epigenetic aging and drug metabolism. We review
current evidence for changes in drug metabolism in normal aging, followed by a description …
current evidence for changes in drug metabolism in normal aging, followed by a description …
Aha1 is an autonomous chaperone for SULT1A1
The cochaperone Aha1 activates HSP90 ATPase to promote the folding of its client proteins;
however, very few client proteins of Aha1 are known. With the use of an ascorbate …
however, very few client proteins of Aha1 are known. With the use of an ascorbate …
[PDF][PDF] IN VIVO PHENOTYPING OF SULT1A ENZYMES IN MAN IMPLICATIONS FOR PRECISION MEDICINE
NCDEF MARTO - 2022 - run.unl.pt
The cytosolic sulfotransferase enzymes (SULT) are products of a diverse gene superfamily
that catalyse sulfoconjugation (or sulfonation)-a relatively understudied topic in the area of …
that catalyse sulfoconjugation (or sulfonation)-a relatively understudied topic in the area of …