Growing cancer incidence and mortality worldwide demands development of accurate
biomarkers to perfect detection, diagnosis, prognostication and monitoring. Urologic …

Genetic changes through allelic loss and nucleic acid or protein modifications are the main
contributors to loss of function of tumor suppressor proteins. In particular, epigenetic …

Background: Breast cancer (BrC) is the most frequent neoplasm in women. New biomarkers,
including aberrant DNA methylation, may improve BrC management. Herein, we evaluated …

Background The rising incidence of renal cell carcinomas (RCC) constitutes a significant
challenge owing to risk of overtreatment. Because aberrant microRNA (miR) promoter …

Purpose Epigenetic alterations have been investigated as prognostic indicators in breast
cancer but their translation into clinical practice has been impeded by a lack of appropriate …

Background In patients with hormone receptor-positive breast cancer, differentiating
between patients with a low and a high risk of recurrence is an ongoing challenge. In current …

Epigenetic gene regulation has influence over a diverse range of cellular functions,
including the maintenance of pluripotency, differentiation, and cellular identity, and is …

Breast cancer (BC) is the most common cancer and second leading cause of cancer
mortality in women worldwide. Validated biomarkers enhance efforts for early detection and …

Abstract Background Esophageal cancer (ECa) is the 7th most incident cancer and the 6th
leading cause of cancer-related death. Most patients are diagnosed with locally advanced or …

Breast cancer (BC) is the most common cancer worldwide. The Kingdom of Saudi Arabia is
no exception, with ever increasing incidence rates. An interesting feature of this disease is …