Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

Hyperpolarized (HP) carbon 13 (13C) MRI is an emerging molecular imaging method that
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …

The current view of diabetic kidney disease, based on meticulously acquired ultrastructural
morphometry and the utility of measuring plasma creatinine and urinary albumin, has been …

This review focuses on MRI contrast agents that are responsive to a change in a
physiological biomarker. The response mechanisms are dependent on six physicochemical …

Dissolution dynamic nuclear polarization (DNP) enables the metabolism of hyperpolarized
13C‐labelled molecules, such as the conversion of [1‐13C] pyruvate to [1‐13C] lactate, to …

With the development of heteronuclear fluorine, sodium, phosphorus, and other probes and
imaging technologies as well as the optimization of magnetic resonance imaging (MRI) …

Hyperpolarized [1-13C] pyruvate is the leading hyperpolarized injectable contrast agent and
is currently under evaluation in clinical trials for molecular imaging of metabolic diseases …

This review provides a comprehensive assessment of the development of hyperpolarized
(HP) carbon-13 metabolic MRI from the early days to the present with a focus on clinical …

Abstract Hyperpolarised MRI with Dynamic Nuclear Polarisation overcomes the fundamental
thermodynamic limitations of conventional magnetic resonance, and is translating to human …

Zero-to ultralow-field (ZULF) nuclear magnetic resonance (NMR) is an emerging tool for
precision chemical analysis. In this work, we study dynamic processes and investigate the …