Total coumarin derivates from Hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement …
W Wang, L Sheng, Y Chen, Z Li, H Wu, J Ma, D Zhang… - Phytomedicine, 2022 - Elsevier
Background Total coumarins extracted from Hydrangea. Paniculata, Sieb (HP) have showed
renal protective effect in several experimental acute and chronic kidney diseases. Purpose …
renal protective effect in several experimental acute and chronic kidney diseases. Purpose …
Developing context appropriate toxicity testing approaches using new alternative methods (NAMs)
ME Andersen, PD McMullen, MB Phillips… - ALTEX-Alternatives to …, 2019 - altex.org
In the past 10 years, the public, private, and non-profit sectors have found agreement that
hazard identification and risk assessment should capitalize on the explosion of knowledge …
hazard identification and risk assessment should capitalize on the explosion of knowledge …
Wrangling whole mixtures risk assessment: Recent advances in determining sufficient similarity
Human health risk assessments for complex mixtures can address real-world exposures and
protect public health. While risk assessors typically prefer whole mixture approaches over …
protect public health. While risk assessors typically prefer whole mixture approaches over …
Evidence for anti-inflammatory effects and modulation of neurotransmitter metabolism by Salvia officinalis L.
G Margetts, S Kleidonas, NS Zaibi, MS Zaibi… - … Medicine and Therapies, 2022 - Springer
Background Cognitive health is of great interest to society, with neuroinflammation and
systemic inflammation age-related risk factors that are linked to declines in cognitive …
systemic inflammation age-related risk factors that are linked to declines in cognitive …
[HTML][HTML] The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when …
L Simms, K Rudd, J Palmer, L Czekala, F Yu… - Current Research in …, 2020 - Elsevier
Abstract devTOX quickPredict (devTOX qP) is a metabolomics biomarker-based assay that
utilises human induced pluripotent stem (iPS) cells to screen for potential early stage …
utilises human induced pluripotent stem (iPS) cells to screen for potential early stage …
[HTML][HTML] 21st century approaches for evaluating exposures, biological activity, and risks of complex substances: workshop highlights
UG Sauer, RA Barter, RA Becker, E Benfenati… - Regulatory Toxicology …, 2020 - Elsevier
Abstract The June 2019 workshop 21st Century Approaches for Evaluating Exposures,
Biological Activity, and Risks of Complex Substances, co-organised by the International …
Biological Activity, and Risks of Complex Substances, co-organised by the International …
[HTML][HTML] Use of a rapid human primary cell-based disease screening model, to compare next generation products to combustible cigarettes
A growing number of public health bodies, regulators and governments around the world
consider electronic vapor products a lower risk alternative to conventional cigarettes. Of …
consider electronic vapor products a lower risk alternative to conventional cigarettes. Of …
[PDF][PDF] 化学品风险评估新技术方法的发展及应用
贾栗， 范瑞棋， 张婉君， 陈义强… - 中国药理学与毒理学 …, 2022 - cjpt.magtechjournal.com
新的化合物不断涌现, 替代方法产生了大量体外测试数据, 迫切需要开发快速高效的用于化学品
风险评估的新技术方法(NAM). NAM 的大规模开展和实施为化学品的危害表征和风险评估提供 …
风险评估的新技术方法(NAM). NAM 的大规模开展和实施为化学品的危害表征和风险评估提供 …
[PDF][PDF] Use of a rapid human primary cell-based disease screening model, to compare next generation products to combustible cigarettes
O Brinster - academia.edu
ABSTRACT A growing number of public health bodies, regulators and governments around
the world consider electronic vapor products a lower risk alternative to conventional …
the world consider electronic vapor products a lower risk alternative to conventional …
Comment on coumarin hazard identification
J Rose, S Felter, S Gadhia, K Joshi… - International …, 2020 - journals.sagepub.com
Recently, Hsieh et al1 reviewed and evaluated the scientific data on carcinogenic potential
of coumarin. The authors examined, among other end points, the active ToxCast high …
of coumarin. The authors examined, among other end points, the active ToxCast high …