Application of machine learning to proteomics data: classification and biomarker identification in postgenomics biology

AL Swan, A Mobasheri, D Allaway… - Omics: a journal of …, 2013 - liebertpub.com
Mass spectrometry is an analytical technique for the characterization of biological samples
and is increasingly used in omics studies because of its targeted, nontargeted, and high …

[HTML][HTML] Dietary considerations in autism spectrum disorders: the potential role of protein digestion and microbial putrefaction in the gut-brain axis

MR Sanctuary, JN Kain, K Angkustsiri… - Frontiers in …, 2018 - frontiersin.org
Children with autism spectrum disorders (ASD), characterized by a range of behavioral
abnormalities and social deficits, display high incidence of gastrointestinal (GI) co …

Sources of technical variability in quantitative LC–MS proteomics: human brain tissue sample analysis

PD Piehowski, VA Petyuk, DJ Orton, F Xie… - Journal of proteome …, 2013 - ACS Publications
To design a robust quantitative proteomics study, an understanding of both the inherent
heterogeneity of the biological samples being studied as well as the technical variability of …

Biogenic carbon dot-based fluorescence-mediated immunosensor for the detection of disease biomarker

A Deb, GR Nalkar, D Chowdhury - Analytica Chimica Acta, 2023 - Elsevier
The dynamic interplay of nanotechnology and immunoassay has unlocked an arena for
developing next-generation techniques to contribute to detecting disease biomarkers …

Label-free optical detection of multiple biomarkers in sweat, plasma, urine, and saliva

P Ray, AJ Steckl - ACS sensors, 2019 - ACS Publications
We report a novel label-free quantitative detection of human performance “stress”
biomarkers in different body fluids based on optical absorbance of the biomarkers in the …

Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020

H Hampel, S Lista, SJ Teipel, F Garaci, R Nisticò… - Biochemical …, 2014 - Elsevier
Recent advances in understanding the molecular mechanisms underlying various paths
toward the pathogenesis of Alzheimer's disease (AD) has begun to provide new insight for …

Differential protein profiling of synovial fluid from rheumatoid arthritis and osteoarthritis patients using LC–MALDI TOF/TOF

J Mateos, L Lourido, P Fernández-Puente… - Journal of …, 2012 - Elsevier
The purpose of this study was to identify those proteins relatively more abundant in the
synovial fluid (SF) of patients suffering from rheumatoid arthritis (RA) and osteoarthritis (OA) …

Blood and plasma-based proteomic biomarker research in Alzheimer's disease

S Lista, F Faltraco, D Prvulovic, H Hampel - Progress in neurobiology, 2013 - Elsevier
Alzheimer's disease (AD) is the most important cause of dementia in the elderly. The
molecular alterations preceding this neurodegenerative pathology may take place even 20 …

Fluorescence sensing of circulating diagnostic biomarkers using molecular probes and nanoparticles

O Tagit, N Hildebrandt - ACS sensors, 2017 - ACS Publications
The interplay of photonics, nanotechnology, and biochemistry has significantly improved the
identification and characterization of multiple types of biomarkers by optical biosensors …

Real-time and label-free detection of the prostate-specific antigen in human serum by a polycrystalline silicon nanowire field-effect transistor biosensor

YW Huang, CS Wu, CK Chuang, ST Pang… - Analytical …, 2013 - ACS Publications
In this research, we used a polycrystalline silicon nanowire field-effect transistor (poly-Si
NWFET) as a biosensor that employs the sidewall spacer technique instead of an expensive …