Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Highlights•Sixteen leading groups review evidence for the therapeutic effects of
agmatine.•Agmatine modulatory action at multiple molecular targets is highlighted.• …

Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …

Background FK506 binding protein 51 (FKBP51) is an Hsp90 co-chaperone and regulator of
the glucocorticoid receptor, and consequently of stress physiology. Clinical studies suggest …

This paper reviews and interprets a method for determining the nutritional value of d-amino
acids, d-peptides, and amino acid derivatives using a growth assay in mice fed a synthetic …

Agmatine, an endogenous polyamine derived from L-arginine, elicits tremendous
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …

Monoamine oxidase (MAO, EC. 1.4. 3.4) has been a drug target for 60 years, with the
primary rationale of developing drugs to treat neuropsychiatric disorders. The biological …

Agmatine, the decarboxylation product of arginine, was largely neglected as an important
player in mammalian metabolism until the mid-1990s, when it was re-discovered as an …

Agmatine is a polyamine that is produced via decarboxylation of l-arginine by the enzyme
arginine decarboxylase. It binds to various receptors and has been accepted as a novel …

Agmatine, an endogenous neuromodulator, is a potential candidate to constitute an
adjuvant/monotherapy for the management of depression. A recent study by our group …