Crosstalk between gut microbiota and host immunity: impact on inflammation and immunotherapy

C Campbell, MR Kandalgaonkar, RM Golonka… - Biomedicines, 2023 - mdpi.com
Gut microbes and their metabolites are actively involved in the development and regulation
of host immunity, which can influence disease susceptibility. Herein, we review the most …

Immunomodulatory biomaterials against bacterial infections: Progress, challenges, and future perspectives

S Zhang, H Yang, M Wang, D Mantovani, K Yang… - The Innovation, 2023 - cell.com
Bacterial infectious diseases are one of the leading causes of death worldwide. Even with
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …

Neutrophils' extracellular trap mechanisms: from physiology to pathology

J Schoen, M Euler, C Schauer, G Schett… - International Journal of …, 2022 - mdpi.com
Neutrophils are an essential part of the innate immune system and the first line of defense
against invading pathogens. They phagocytose, release granular contents, produce reactive …

COVID-19 vaccination in patients with malignancy; a systematic review and meta-analysis of the efficacy and safety

SA Javadinia, K Alizadeh, MS Mojadadi… - Frontiers in …, 2022 - frontiersin.org
Background Data on the efficacy and safety of COVID-19 vaccines in patients with
malignancy are immature. In this paper, we assessed the literature involving the use of …

Sustained viral suppression with dolutegravir monotherapy over 192 weeks in patients starting combination antiretroviral therapy during primary human …

E West, M Zeeb, C Grube, H Kuster… - Clinical Infectious …, 2023 - academic.oup.com
Background Starting combination antiretroviral therapy (cART) during primary human
immunodeficiency virus type 1 (HIV-1) infection results in a smaller HIV-1 latent reservoir …

Platelet-neutrophil interaction in COVID-19 and vaccine-induced thrombotic thrombocytopenia

J Hirsch, G Uzun, J Zlamal, A Singh… - Frontiers in …, 2023 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is known to commonly induce a thrombotic diathesis,
particularly in severely affected individuals. So far, this COVID-19-associated coagulopathy …

Aberrant neutrophil degranulation in hospitalized patients with COVID‐19 partially remains for 6 months

FMJ Hafkamp, EWM Taanman‐Kueter… - European Journal of …, 2024 - Wiley Online Library
Neutrophils are important players in COVID‐19, contributing to tissue damage by release of
inflammatory mediators, including ROS and neutrophil elastase. Longitudinal studies on the …

The role of KH-type splicing regulatory protein (KSRP) for immune functions and tumorigenesis

KA Palzer, V Bolduan, R Käfer, H Kleinert, M Bros… - Cells, 2022 - mdpi.com
Post-transcriptional control of gene expression is one important mechanism that enables
stringent and rapid modulation of cytokine, chemokines or growth factors expression, all …

CXCR2 Is Essential for Radiation‐Induced Intestinal Injury by Initiating Neutrophil Infiltration

J Hu, Q Ji, F Chen, X Gong, C Chen… - Journal of …, 2022 - Wiley Online Library
Neutrophils, known as an important part of the immune system, are the most abundant
leukocyte population in peripheral blood, but excessive recruitment will lead to tissue/organ …

RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells

T Yang, C Xiang, X Wang, Q Li, S Lei, K Zhang… - Cell Death …, 2024 - nature.com
Acute lung injury (ALI) is an acute and progressive hypoxic respiratory failure that could
progress to acute respiratory distress syndrome (ARDS) with a high mortality rate, thus …