Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis

G Hindy, DJ Tyrrell, A Vasbinder, C Wei… - The Journal of …, 2022 - Am Soc Clin Investig
People with kidney disease are disproportionately affected by atherosclerosis for unclear
reasons. Soluble urokinase plasminogen activator receptor (suPAR) is an immune-derived …

Sudden Cardiac Death (SCD)–risk stratification and prediction with molecular biomarkers

J Osman, SC Tan, PY Lee, TY Low, R Jamal - Journal of biomedical …, 2019 - Springer
Sudden cardiac death (SCD) is a sudden, unexpected death that is caused by the loss of
heart function. While SCD affects many patients suffering from coronary artery diseases …

Independent impact of periodontitis and cardiovascular disease on elevated soluble urokinase‐type plasminogen activator receptor (suPAR) levels

G Isola, A Polizzi, A Alibrandi… - Journal of …, 2021 - Wiley Online Library
Background Previous studies have demonstrated that a soluble urokinase‐type
plasminogen activator receptor (suPAR) plays an essential function in leukocytes and …

[HTML][HTML] Soluble urokinase plasminogen activator receptor as a diagnostic and prognostic biomarker in cardiac disease

D Velissaris, N Zareifopoulos, I Koniari… - Journal of clinical …, 2021 - ncbi.nlm.nih.gov
This review summarizes the published literature referring to the use and validity of the
biomarker soluble urokinase plasminogen activator receptor (suPAR) when used for the …

[HTML][HTML] Aggregate clinical and biomarker-based model predicts adverse outcomes in patients with coronary artery disease

SR Desai, DS Dhindsa, YA Ko, PB Sandesara… - The American journal of …, 2023 - Elsevier
Despite guideline-based therapy, patients with coronary artery disease (CAD) are at widely
variable risk for cardiovascular events. This variability demands a more individualized risk …

Cohort profile: the emory cardiovascular biobank (EMCAB)

YA Ko, S Hayek, P Sandesara, AS Tahhan… - BMJ open, 2017 - bmjopen.bmj.com
Purpose The Emory Cardiovascular Biobank (EmCAB) is an ongoing prospective registry of
patients undergoing cardiac catheterisation, which was established to identify novel factors …

Immune activation mediates the Association of Advanced Hepatic Fibrosis with Adverse Outcomes in patients with coronary artery disease

V Jain, A Mehta, TB Lee, C Liu, NWS Chew… - Journal of the …, 2023 - Am Heart Assoc
Background Literature suggests a bidirectional association between advanced hepatic
fibrosis (AHF) and coronary artery disease (CAD). We evaluated the association of AHF with …

[HTML][HTML] Derivation and validation of a simple inflammation-based risk score system for predicting in-hospital mortality in acute coronary syndrome patients

H González-Pacheco, R Bojalil… - Journal of …, 2019 - Elsevier
Background Accurate assessment of inflammatory status of patients during acute coronary
syndrome (ACS) has become of great importance in their risk classification and in the …

Soluble urokinase-type plasminogen activator receptor in black Americans with CKD

S Luo, J Coresh, A Tin, CM Rebholz… - Clinical Journal of the …, 2018 - journals.lww.com
Results At baseline, the median suPAR was 4462 pg/ml, mean measured GFR was 46
ml/min per 1.73 m 2, and median 24-hour urine protein-to-creatinine ratio was 80 mg/g. After …

Soluble urokinase‐type plasminogen activator receptor and high‐sensitivity troponin levels predict outcomes in nonobstructive coronary artery disease

A Al‐Badri, AS Tahhan, N Sabbak… - Journal of the …, 2020 - Am Heart Assoc
Background Multiple biomarkers have been independently and additively associated with
major adverse cardiovascular events in patients with coronary artery disease. We …