The syncytiotrophoblast (SCT) is the outer layer of placenta which is in direct contact with
maternal blood. As such it is uniquely positioned to alter maternal hemostasis and …

Endogenous microRNAs (miRNAs) post-transcriptionally regulate mRNA and protein
expression during tissue development and function. Whereas adaptation to environmental …

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A proteomics screen of human placental microvillous syncytiotrophoblasts (STBs) revealed
the expression of dysferlin (DYSF), a plasma membrane repair protein associated with …

Tyrosine phosphorylation plays a major role in controlling many biological processes in
different cell types. Src family kinases (SFKs) are one of the most studied groups of tyrosine …

Human placental villi are surfaced by the syncytiotrophoblast, a multinucleated, epithelial-
cell layer that functions in maternal–fetal exchange. Mononucleated cytotrophoblasts are …

Introduction Fibrin deposition in placenta is a common phenomenon which can be triggered
by villous injury and coagulation activation. Fibrin abnormalities (hypo/dysfibrinogenemia) …

Preeclampsia is associated with an increased release of factors from the placental
syncytium into maternal blood, including the antiangiogenic factors soluble fms‐like tyrosine …

The parenchyma of the placenta comprises the villous trees that provide an extensive
surface area to facilitate maternal-fetal exchange. This chapter introduces the different cell …

Dysferlin (DYSF) and myoferlin (MYOF), members of the ferlin family of membrane proteins,
are co-expressed in human placental syncytiotrophoblast (STB). Although the role of these …