Animal models of inflammation for screening of anti-inflammatory drugs: implications for the discovery and development of phytopharmaceuticals

KR Patil, UB Mahajan, BS Unger, SN Goyal… - International journal of …, 2019 - mdpi.com
Inflammation is one of the common events in the majority of acute as well as chronic
debilitating diseases and represent a chief cause of morbidity in today's era of modern …

Biological activity of algal derived carrageenan: A comprehensive review in light of human health and disease

B Pradhan, JS Ki - International Journal of Biological Macromolecules, 2023 - Elsevier
Carrageenans are a family of natural linear sulfated polysaccharides derived from red
seaweeds and used as a common food additive. Carrageenan's properties, impact on …

[HTML][HTML] Carrageenan: a review

J Necas, L Bartosikova - Veterinarni medicina, 2013 - vetmed.agriculturejournals.cz
Carrageenan is a natural carbohydrate (polysaccharide) obtained from edible red
seaweeds. The name Carrageenan is derived from the Chondrus crispus species of …

Central and peripheral pain intervention by Ophiorrhiza rugosa leaves: potential underlying mechanisms and insight into the role of pain modulators

MNU Chy, M Adnan, MR Chowdhury, E Pagano… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Ophiorrhiza rugosa var. prostrata is a traditional medicinal
plant used by the indigenous and local tribes (Chakma, Marma and Tanchangya) of …

Anti-inflammatory effects of compounds alpha-humulene and (−)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea

ES Fernandes, GF Passos, R Medeiros… - European journal of …, 2007 - Elsevier
This study evaluated the anti-inflammatory properties of two sesquiterpenes isolated from
Cordia verbenacea's essential oil, α-humulene and (−)-trans-caryophyllene. Our results …

[HTML][HTML] Antioxidant and Anti-Inflammatory Effects of Zingiber officinale roscoe and Allium subhirsutum: In Silico, Biochemical and Histological Study

N Zammel, M Saeed, N Bouali, S Elkahoui, JM Alam… - Foods, 2021 - mdpi.com
In this study, the antioxidant and anti-inflammatory effects of Zingiber officinale roscoe and
Allium subhirsutum aqueous extracts were examined in a carrageenan-induced acute …

Small molecule disruption of G protein βγ subunit signaling inhibits neutrophil chemotaxis and inflammation

DM Lehmann, A Seneviratne, AV Smrcka - Molecular pharmacology, 2008 - ASPET
G protein βγ subunit-dependent signaling is important for chemoattractant-dependent
leukocyte chemotaxis. Selective small molecule targeting of phosphoinositide 3-kinase (PI3 …

Carvacrol attenuates mechanical hypernociception and inflammatory response

AG Guimarães, MA Xavier, MT de Santana… - Naunyn-Schmiedeberg's …, 2012 - Springer
Carvacrol is a phenolic monoterpene present in the essential oil of the family Lamiaceae, as
in the genera Origanum and Thymus. We previously reported that carvacrol is effective as an …

Animal models as tools to investigate antidiabetic and anti‐inflammatory plants

M Eddouks, D Chattopadhyay… - Evidence‐based …, 2012 - Wiley Online Library
Plants have been historically used for diabetes treatment and related anti‐inflammatory
activity throughout the world; few of them have been validated by scientific criteria. Recently …

Akt1 is critical for acute inflammation and histamine-mediated vascular leakage

A Di Lorenzo, C Fernández-Hernando… - Proceedings of the …, 2009 - National Acad Sciences
Akt1 is implicated in cell metabolism, survival migration, and gene expression; however, little
is known about the role of specific Akt isoforms during inflammation in vivo. Thus, we directly …