Vaccine-associated enhanced disease and pathogenic human coronaviruses

C Gartlan, T Tipton, FJ Salguero, Q Sattentau… - Frontiers in …, 2022 - frontiersin.org
Vaccine-associated enhanced disease (VAED) is a difficult phenomenon to define and can
be confused with vaccine failure. Using studies on respiratory syncytial virus (RSV) …

The COVID-19 vaccines: recent development, challenges and prospects

Y Yan, Y Pang, Z Lyu, R Wang, X Wu, C You, H Zhao… - Vaccines, 2021 - mdpi.com
The highly infectious coronavirus disease 2019 (COVID-19) associated with the pathogenic
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to become a …

Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

DT Skelly, AC Harding, J Gilbert-Jaramillo… - Nature …, 2021 - nature.com
The extent to which immune responses to natural infection with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and immunization with vaccines protect against …

Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant

KA Ryan, KR Bewley, RJ Watson, C Burton… - PLoS …, 2023 - journals.plos.org
The mutation profile of the SARS-CoV-2 Omicron (lineage BA. 1) variant posed a concern for
naturally acquired and vaccine-induced immunity. We investigated the ability of prior …

Considerations for the feasibility of neutralizing antibodies as a surrogate endpoint for COVID-19 vaccines

J Liu, Q Mao, X Wu, Q He, L Bian, Y Bai… - Frontiers in …, 2022 - frontiersin.org
To effectively control and prevent the pandemic of coronavirus disease 2019 (COVID-19),
suitable vaccines have been researched and developed rapidly. Currently, 31 COVID-19 …

Influence of aerosol delivered BCG vaccination on immunological and disease parameters following SARS-CoV-2 challenge in rhesus macaques

AD White, L Sibley, C Sarfas, AL Morrison… - Frontiers in …, 2022 - frontiersin.org
The tuberculosis vaccine, Bacille Calmette-Guerin (BCG), also affords protection against
non-tuberculous diseases attributable to heterologous immune mechanisms such as trained …

Overview of nonhuman primate models of SARS-CoV-2 infection

AM Trichel - Comparative Medicine, 2021 - ingentaconnect.com
COVID-19, the disease caused by the SARS-CoV-2 betacoronavirus, was declared a
pandemic by the World Health Organization on March 11, 2020. Since then, SARS-CoV-2 …

Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model

A Patel, JN Walters, EL Reuschel, K Schultheis… - Cell Reports …, 2021 - cell.com
Summary Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has
had a dramatic global impact on public health and social and economic infrastructures …

SARS-CoV-2 DNA vaccine INO-4800 induces durable immune responses capable of being boosted in a phase 1 open-label trial

KA Kraynyak, E Blackwood, J Agnes… - The Journal of …, 2022 - academic.oup.com
Background Additional severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccines that are safe and effective as primary vaccines and boosters remain urgently …

Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates

MA Stammes, JH Lee, L Meijer, T Naninck… - Trends in Molecular …, 2022 - cell.com
Chest X-ray (CXR), computed tomography (CT), and positron emission tomography–
computed tomography (PET-CT) are noninvasive imaging techniques widely used in human …