The clinical promise of biomarkers of synapse damage or loss in Alzheimer's disease
Background Synapse damage and loss are fundamental to the pathophysiology of
Alzheimer's disease (AD) and lead to reduced cognitive function. The goal of this review is to …
Alzheimer's disease (AD) and lead to reduced cognitive function. The goal of this review is to …
Brain networks and α-oscillations: structural and functional foundations of cognitive control
S Sadaghiani, A Kleinschmidt - Trends in cognitive sciences, 2016 - cell.com
The most salient electrical signal measured from the human brain is the α-rhythm, neural
activity oscillating at∼ 100ms intervals. Recent findings challenge the longstanding dogma …
activity oscillating at∼ 100ms intervals. Recent findings challenge the longstanding dogma …
Increasing brain gamma activity improves episodic memory and restores cholinergic dysfunction in Alzheimer's disease
Objective This study aimed to assess whether non‐invasive brain stimulation with
transcranial alternating current stimulation at gamma‐frequency (γ‐tACS) applied over the …
transcranial alternating current stimulation at gamma‐frequency (γ‐tACS) applied over the …
Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: recommendations of an expert panel
Abstract The Electrophysiology Professional Interest Area (EPIA) and Global Brain
Consortium endorsed recommendations on candidate electroencephalography (EEG) …
Consortium endorsed recommendations on candidate electroencephalography (EEG) …
Complexity analysis of EEG, MEG, and fMRI in mild cognitive impairment and Alzheimer's disease: a review
J Sun, B Wang, Y Niu, Y Tan, C Fan, N Zhang, J Xue… - Entropy, 2020 - mdpi.com
Alzheimer's disease (AD) is a degenerative brain disease with a high and irreversible
incidence. In recent years, because brain signals have complex nonlinear dynamics, there …
incidence. In recent years, because brain signals have complex nonlinear dynamics, there …
The cholinergic brain in Parkinson's disease
The central cholinergic system includes the basal forebrain nuclei, mainly projecting to the
cortex, the mesopontine tegmental nuclei, mainly projecting to the thalamus and subcortical …
cortex, the mesopontine tegmental nuclei, mainly projecting to the thalamus and subcortical …
Dysfunctional brain dynamics and their origin in Lewy body dementia
Lewy body dementia includes dementia with Lewy bodies and Parkinson's disease
dementia and is characterized by transient clinical symptoms such as fluctuating cognition …
dementia and is characterized by transient clinical symptoms such as fluctuating cognition …
In vivo tau pathology is associated with synaptic loss and altered synaptic function
EM Coomans, DN Schoonhoven, H Tuncel… - Alzheimer's research & …, 2021 - Springer
Background The mechanism of synaptic loss in Alzheimer's disease is poorly understood
and may be associated with tau pathology. In this combined positron emission tomography …
and may be associated with tau pathology. In this combined positron emission tomography …
Cholinergic white matter pathways in dementia with Lewy bodies and Alzheimer's disease
Patients who have dementia with Lewy bodies and Alzheimer's disease show early
degeneration of the cholinergic nucleus basalis of Meynert. However, how white matter …
degeneration of the cholinergic nucleus basalis of Meynert. However, how white matter …
EEG alpha reactivity and cholinergic system integrity in Lewy body dementia and Alzheimer's disease
Background Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLB)
and Parkinson's disease dementia (PDD), is characterised by marked deficits within the …
and Parkinson's disease dementia (PDD), is characterised by marked deficits within the …