Phylogenetic classification and functional review of autotransporters
Autotransporters are the core component of a molecular nano-machine that delivers cargo
proteins across the outer membrane of Gram-negative bacteria. Part of the type V secretion …
proteins across the outer membrane of Gram-negative bacteria. Part of the type V secretion …
Serine proteases autotransporter of Enterobacteriaceae: Structures, subdomains, motifs, functions, and targets
F Navarro‐Garcia - Molecular Microbiology, 2023 - Wiley Online Library
Serine protease autotransporters of Enterobacteriaceae (SPATE) constitute a superfamily of
virulence factors, resembling the trypsin‐like superfamily of serine proteases. SPATEs …
virulence factors, resembling the trypsin‐like superfamily of serine proteases. SPATEs …
Serine Protease Autotransporters of the Enterobacteriaceae (SPATEs): Out and About and Chopping It Up
Autotransporters are secreted proteins with multiple functions produced by a variety of Gram-
negative bacteria. In Enterobacteriaceae, a subgroup of these autotransporters are the …
negative bacteria. In Enterobacteriaceae, a subgroup of these autotransporters are the …
EspC, an autotransporter protein secreted by enteropathogenic Escherichia coli, causes apoptosis and necrosis through caspase and calpain activation, including …
A Serapio-Palacios, F Navarro-Garcia - MBio, 2016 - Am Soc Microbiol
Enteropathogenic Escherichia coli (EPEC) has the ability to antagonize host apoptosis
during infection through promotion and inhibition of effectors injected by the type III secretion …
during infection through promotion and inhibition of effectors injected by the type III secretion …
A novel mechanism for protein delivery by the type 3 secretion system for extracellularly secreted proteins
F Tejeda-Dominguez, J Huerta-Cantillo… - MBio, 2017 - Am Soc Microbiol
The type 3 secretion system (T3SS) is essential for bacterial virulence through delivering
effector proteins directly into the host cytosol. Here, we identified an alternative delivery …
effector proteins directly into the host cytosol. Here, we identified an alternative delivery …
Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function
Autotransporters (ATs) are a large family of bacterial secreted and outer membrane proteins
that encompass a wide range of enzymatic activities frequently associated with pathogenic …
that encompass a wide range of enzymatic activities frequently associated with pathogenic …