Despite significant advances in the field of cancer immunotherapy, the majority of patients
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …

Dendritic cells (DCs) possess the ability to integrate information about their environment and
communicate it to other leukocytes, shaping adaptive and innate immunity. Over the years, a …

Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …

The presentation of exogenous antigens on MHC class I molecules, known as cross-
presentation, is essential for the initiation of CD8+ T cell responses. In vivo, cross …

Neuroinflammation is a major contributor to disease progression in Alzheimer's disease
(AD) and is characterized by the activity of brain resident glial cells, in particular microglia …

Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

As dendritic cells (DC) are rare populations in all organs, their generation from
hematopoietic precursors in large quantities has proven critical to study their biology. From …

Dendritic cells (DCs) are essential mediators of innate and adaptive immune responses.
Study of these critical cells has been complicated by their similarity to other hematopoietic …

A properly functioning adaptive immune system signifies the best features of life. It is diverse
beyond compare, tolerant without fail, and capable of behaving appropriately with a myriad …