There have been significant advances in our understanding of mononuclear nonheme iron
oxygenases since our 1996 Chemical Reviews article, 1 promoted in large part by the many …

Fe (II)/α-ketoglutarate (αKG)-dependent hydroxylases catalyze an amazing diversity of
reactions that result in protein side-chain modifications, repair of alkylated DNA/RNA …

High-valent non-heme iron–oxo intermediates have been proposed for decades as the key
intermediates in numerous biological oxidation reactions. In the past three years, the first …

New catalytic synthetic methods in organic chemistry that satisfy increasingly stringent
environmental constraints are in great demand by the pharmaceutical and chemical …

Abstract The 2-His-1-carboxylate facial triad is a widely used scaffold to bind the iron center
in mononuclear nonheme iron enzymes for activating dioxygen in a variety of oxidative …

Covering: up to June 2006We review the literature on the enzymes, genes, and whole gene
clusters underlying natural product biosyntheses and their regulation in filamentous fungi …

Iron-containing enzymes are one of Nature's main means of effecting key biological
transformations. The mononuclear non-heme iron oxygenases and oxidases have received …

Mononuclear non-heme ferrous iron dependent oxygenases and oxidases constitute an
extended enzyme family that catalyze a wide range of oxidation reactions. The largest …

The domain of unknown function 692 (DUF692) is an emerging family of post-translational
modification enzymes involved in the biosynthesis of ribosomally synthesized and post …

Natural products containing carbon-phosphorus bonds (phosphonic and phosphinic acids)
have found widespread use in medicine and agriculture. Recent years have seen a …