Advances in dry eye disease treatment

EC O'Neil, M Henderson… - Current opinion in …, 2019 - journals.lww.com
Clinicians have more options at their disposal in the treatment of dry eye disease than ever
before, including topical medications and devices. SYNOPSIS In this article, we review …

[HTML][HTML] Dry eye disease associated with meibomian gland dysfunction: focus on tear film characteristics and the therapeutic landscape

JD Sheppard, KK Nichols - Ophthalmology and Therapy, 2023 - Springer
Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of
evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum …

Alternative therapies for dry eye disease

R Mittal, S Patel, A Galor - Current opinion in ophthalmology, 2021 - journals.lww.com
Alternative therapies for dry eye disease : Current Opinion in Ophthalmology Alternative
therapies for dry eye disease : Current Opinion in Ophthalmology Log in or Register Subscribe …

[HTML][HTML] Varenicline solution nasal spray: a review in dry eye disease

JE Frampton - Drugs, 2022 - Springer
Increasing endogenous tear film production via pharmacological neuroactivation of the
nasolacrimal reflex [NLR; also known as the trigeminal parasympathetic pathway (TPP)] is a …

Neuropathic ocular surface pain: emerging drug targets and therapeutic implications

S Patel, R Mittal, KD Sarantopoulos… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Dysfunction at various levels of the somatosensory system can lead to ocular
surface pain with a neuropathic component. Compared to nociceptive pain (due to noxious …

Dry eye disease, a prominent manifestation of systemic autoimmune disorders

A Bustamante-Arias, RE Ruiz Lozano… - European Journal …, 2022 - journals.sagepub.com
Objectives Dry eye disease (DED) is arguably the most frequent ocular disease encountered
in ophthalmic clinical practice. DED is frequently an underestimated condition causing a …

Nicotinic acetylcholine receptor stimulation: A new approach for stimulating tear secretion in dry eye disease

SC Pflugfelder, A Cao, A Galor, KK Nichols, NA Cohen… - The ocular …, 2022 - Elsevier
Tear secretion is regulated by the lacrimal functional unit consisting of afferent and efferent
nerve innervation. The afferent arm consists of trigeminal nociceptors on the ocular surface …

Emerging therapies for dry eye disease

L Mason, S Jafri, I Dortonne… - Expert opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction Dry Eye Disease (DED) is defined as a multifactorial disease of the
ocular surface characterized by a loss of homeostasis of the tear film, and a vicious cycle of …

Neurostimulation for dry eye disease

N Erdinest, S Pincovich, N London… - Current Opinion in …, 2022 - journals.lww.com
Neurostimulation for dry eye disease : Current Opinion in Allergy and Clinical Immunology
Neurostimulation for dry eye disease : Current Opinion in Allergy and Clinical Immunology Log …

[HTML][HTML] Effectiveness of transcutaneous electrical stimulation combined with artificial tears for the treatment of dry eye: A randomized controlled trial

MM Cai, J Zhang - Experimental and Therapeutic …, 2020 - spandidos-publications.com
There is currently no available cure or universally effective treatment for dry eye (DE). The
aim of the present study was to investigate the clinical efficacy of transcutaneous electrical …