Anti–glomerular basement membrane (anti-GBM) disease is a rare small vessel vasculitis
that affects the capillary beds of the kidneys and lungs. It is an archetypic autoimmune …

Defects in type IV collagen, a collagenous protein involved in the formation of basement
membranes, have been implicated in hereditary Alport's syndrome and acquired …

Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Classic anti-glomerular basement membrane (GBM) disease presents with rapidly
progressive glomerulonephritis (GN) with or without pulmonary hemorrhage. On biopsy …

A 47-year-old white man who worked as a professional musician presented to his general
practitioner with a 3-week history of malaise, loss of appetite, slight weight loss, and dark …

Anti-glomerular basement membrane (anti-GBM) disease is a rare life-threatening small-
vessel vasculitis that typically affects the capillaries of kidneys and lungs, with most of …

Background Patients with anti-glomerular basement membrane (GBM) disease are at
increased risk of morbidity and mortality from renal failure, pulmonary haemorrhage or …

Autoantibodies against a constituent of the glomerular basement membrane (GBM), the α3-
chain of type IV collagen, can cause both rapidly progressive glomerulonephritis and …

The KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases
represents the first update to this set of recommendations since the initial set of KDIGO …

Antiglomerular basement membrane (anti-GBM) disease is an autoimmune disorder that
mostly presents as raised titers of antibodies against the GBM, rapidly progressive …