[HTML][HTML] Nitrate: the Dr. Jekyll and Mr. Hyde of human health?

CP Bondonno, L Zhong, NP Bondonno, M Sim… - Trends in Food Science …, 2023 - Elsevier
Background Dietary nitrate has a controversial role in human health. For over half a century,
the nitrate content of the three major dietary sources–vegetables, meat, and water–has been …

Critical review of major sources of human exposure to N-nitrosamines

AJ Gushgari, RU Halden - Chemosphere, 2018 - Elsevier
More than 24 N-nitrosamine compounds contribute to the total N-nitrosamine (TNA) burden
monitored routinely to assess human exposure to this important group of known and …

Regulatory updates and analytical methodologies for nitrosamine impurities detection in sartans, ranitidine, nizatidine, and metformin along with sample preparation …

KM Shaik, B Sarmah, GS Wadekar… - Critical reviews in …, 2022 - Taylor & Francis
Nitrosamine impurities have been detected in various pharmaceutical products in recent
days. Various sartans, ranitidine, nizatidine, and metformin have been recalled from the …

The nitrosamine “saga”: lessons learned from five years of scrutiny

R Nudelman, G Kocks, B Mouton… - … Process Research & …, 2023 - ACS Publications
The onset of the N-nitrosamine (NA) saga in 2018 was chiefly related to certain small dialkyl
N-nitrosamines originating from the synthesis of the active pharmaceutical ingredient (API) …

The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment

IMCM Rietjens, A Michael, HM Bolt, B Siméon… - Archives of …, 2022 - Springer
The “totality” of the human exposure is conceived to encompass life-associated endogenous
and exogenous aggregate exposures. Process-related contaminants (PRCs) are not only …

GAC to BAC: does it make chloraminated drinking water safer?

AA Cuthbertson, SY Kimura, HK Liberatore… - Water Research, 2020 - Elsevier
Biological activated carbon (BAC) is widely used as a polishing step at full-scale drinking
water plants to remove taste and odor compounds and assimilable organic carbon. BAC …

Formation mechanism and control strategies of N-nitrosodimethylamine (NDMA) formation during ozonation

Y Song, S Feng, W Qin, J Li, C Guan, Y Zhou… - Science of The Total …, 2022 - Elsevier
This review summarizes major findings over the last decade related to N-
nitrosodimethylamine (NDMA) formed upon ozonation, which was regarded as highly toxic …

A novel molecularly imprinted polymer-solid phase extraction method coupled with high performance liquid chromatography tandem mass spectrometry for the …

Z Li, J Wang, X Chen, S Hu, T Gong, Q Xian - Food chemistry, 2019 - Elsevier
Nitrosamines (NAs) as a group of emerging nitrogenous disinfection byproducts were
present in drinking water at ng/L levels. Accurate measurements of NAs at such a trace level …

N‐nitrosodimethylamine‐Contaminated Valsartan and Risk of Cancer: A Nationwide Study of 1.4 Million Valsartan Users

I Mansouri, J Botton, L Semenzato… - Journal of the …, 2022 - Am Heart Assoc
Background Since July 2018, numerous lots of valsartan have been found to be
contaminated with N‐nitrosodimethylamine (NDMA). We aimed to assess the association …

Direct potable reuse: are we ready? A review of technological, economic, and environmental considerations

AA Keller, Y Su, D Jassby - ACS ES&T Engineering, 2021 - ACS Publications
Meeting future water demand will require serious consideration of direct potable reuse
(DPR) for many water agencies. There has been tremendous progress in the technologies …