Traditional ophthalmic drugs, such as eye drops, gels and ointments, are accompanied by
many problems, including low bioavailability and potential drug side effects. Innovative …

Pirfenidone, initially indicated for lung fibrosis, has gone beyond its original purpose, and
shown promise in eye care. This detailed review tracks its evolution from lung treatment to …

Dynamic emergence of microbial keratitis (MK) requires a promising therapeutic arsenal of
antifungal and antibacterial agents like voriconazole (VCZ) and moxifloxacin (MOXI) …

A novel, quick and precise RP‐UHPLC analytical method for the simultaneous
determination of moxifloxacin (MFX), voriconazole (VCZ) and pirfenidone (PIR) was …

Fibrosis is the result of chronic inflammation and is known to pathologically occur in many
organs and systems. Pirfenidone (PFD) is an anti-fibrotic known for its use in idiopathic …

Chemical injury by alkali burn is a major cause of corneal blindness in the clinical setting.
Current management advocates multiple therapies aimed to prevent inflammation, initiate …

Proliferative diabetic retinopathy (PDR), proliferative vitreoretinopathy (PVR), and
neovascular age-related macular degeneration (nAMD) are among the leading causes of …

Background Pirfenidone has demonstrated significant anti‐inflammatory and antifibrotic
effects in both animal models and some clinical trials. Its potential for antifibrotic activity …

Nowadays, ocular drug delivery still remains a challenge, since the conventional dosage
forms used for anterior and posterior ocular disease treatments, such as topical, systemic …

Aims To evaluate the efficacy and safety of intravitreal triamcinolone acetonide (TA) injection
at the end of emergency surgery for open globe injury (OGI) to suppress traumatic …