Leishmaniasis–current chemotherapy and recent advances in the search for novel drugs

SL Croft, GH Coombs - Trends in parasitology, 2003 - cell.com
The chemotherapy currently available for leishmaniasis is far from satisfactory. Resistance to
the pentavalent antimonials, which have been the recommended drugs for the treatment of …

Amphotericin B: A drug of choice for Visceral Leishmaniasis

S Kumari, V Kumar, RK Tiwari, V Ravidas, K Pandey… - Acta Tropica, 2022 - Elsevier
Visceral leishmaniasis or Kala-azar is a vector-borne disease caused by an intracellular
parasite of the genus leishmania. In India, Amphotericin B (AmB) is a first-line medication for …

Chemotherapy in the treatment and control of leishmaniasis

J Alvar, S Croft, P Olliaro - Advances in parasitology, 2006 - Elsevier
Drugs remain the most important tool for the treatment and control of both visceral and
cutaneous leishmaniasis. Although there have been several advances in the past decade …

Chemotherapy of leishmaniasis: past, present and future

J Mishra, A Saxena, S Singh - Current medicinal chemistry, 2007 - ingentaconnect.com
Leishmaniasis is a parasitic disease caused by hemoflagellate, Leishmania spp. The
parasite is transmitted by the bite of an infected female phlebotomine sandfly. The disease is …

Liposomal amphotericin B as a treatment for human leishmaniasis

M Balasegaram, K Ritmeijer, MA Lima… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Leishmaniasis is a parasitic disease transmitted by phlebotomine sandflies.
Between 700,000 and 1.2 million cases of cutaneous leishmaniasis and between 200,000 …

Antileishmanial drug discovery: Comprehensive review of the last 10 years

JN Sangshetti, FAK Khan, AA Kulkarni, R Arote… - Rsc Advances, 2015 - pubs.rsc.org
Leishmaniasis, a group of diseases caused by hemoflagellate obligate intracellular protozoa
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …

Clinical and experimental advances in treatment of visceral leishmaniasis

HW Murray - Antimicrobial agents and chemotherapy, 2001 - Am Soc Microbiol
Visceral leishmaniaisis (kala-azar) is a disseminated protozoal infection, transmitted by
sandffy bite, in which macrophages of the liver, spleen, and bone marrow are preferentially …

Treatment options for visceral leishmaniasis: a systematic review of clinical studies done in India, 1980–2004

PL Olliaro, PJ Guerin, S Gerstl… - The Lancet infectious …, 2005 - thelancet.com
The state of Bihar in India carries the largest share of the world's burden of antimony-
resistant visceral leishmaniasis. We analysed clinical studies done in Bihar with different …

[HTML][HTML] Current status of nanoscale drug delivery and the future of nano-vaccine development for leishmaniasis–A review

P Prasanna, P Kumar, S Kumar, VK Rajana… - Biomedicine & …, 2021 - Elsevier
The study of tropical diseases like leishmaniasis, a parasitic disease, has not received much
attention even though it is the second-largest infectious disease after malaria. As per the …

Species-directed therapy for leishmaniasis in returning travellers: a comprehensive guide

CJ Hodiamont, PA Kager, A Bart… - PLoS neglected …, 2014 - journals.plos.org
Background Leishmaniasis is increasingly reported among travellers. Leishmania species
vary in sensitivity to available therapies. Fast and reliable molecular techniques have made …