Imaging correlates of adult glioma genotypes

M Smits, MJ van den Bent - Radiology, 2017 - pubs.rsna.org
Primary brain tumors, most commonly gliomas, are histopathologically typed and graded as
World Health Organization (WHO) grades I–IV according to increasing degrees of …

Diffusion-weighted imaging in cancer: physical foundations and applications of restriction spectrum imaging

NS White, CR McDonald, N Farid, J Kuperman… - Cancer research, 2014 - AACR
Diffusion-weighted imaging (DWI) has been at the forefront of cancer imaging since the early
2000s. Before its application in clinical oncology, this powerful technique had already …

Multimodality brain tumor imaging: MR imaging, PET, and PET/MR imaging

JR Fink, M Muzi, M Peck, KA Krohn - Journal of Nuclear Medicine, 2015 - Soc Nuclear Med
Standard MR imaging and CT are routinely used for anatomic diagnosis in brain tumors.
Pretherapy planning and posttreatment response assessments rely heavily on gadolinium …

Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T

D Paech, J Windschuh, J Oberhollenzer… - Neuro …, 2018 - academic.oup.com
Background Early identification of prognostic superior characteristics in glioma patients such
as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase …

Radiomics signature: a potential biomarker for the prediction of MGMT promoter methylation in glioblastoma

Y Xi, F Guo, Z Xu, C Li, W Wei, P Tian… - Journal of Magnetic …, 2018 - Wiley Online Library
Background In glioblastoma (GBM), promoter methylation of the DNA repair gene O‐
methylguanine‐DNA methyltransferase (MGMT) is associated with beneficial chemotherapy …

Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II–III diffuse gliomas

K Leu, GA Ott, A Lai, PL Nghiemphu, WB Pope… - Journal of neuro …, 2017 - Springer
The value of perfusion and diffusion-weighted MRI in differentiating histological subtypes
according to the 2007 WHO glioma classification scheme (ie astrocytoma vs …

Lessons from anti–vascular endothelial growth factor and anti–vascular endothelial growth factor receptor trials in patients with glioblastoma

C Lu-Emerson, DG Duda, KE Emblem… - Journal of Clinical …, 2015 - ascopubs.org
Treatment of glioblastoma (GBM), the most common primary malignant brain tumor in adults,
remains a significant unmet need in oncology. Historically, cytotoxic treatments provided …

Differentiating tumor progression from pseudoprogression in patients with glioblastomas using diffusion tensor imaging and dynamic susceptibility contrast MRI

S Wang, M Martinez-Lage, Y Sakai… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Early assessment of treatment response is critical in
patients with glioblastomas. A combination of DTI and DSC perfusion imaging parameters …

Conventional and advanced magnetic resonance imaging in patients with high-grade glioma

BP Whitney, G Brandal - … of the Italian Association of Nuclear …, 2018 - pmc.ncbi.nlm.nih.gov
Magnetic resonance imaging is integral to the care of patients with high-grade gliomas.
Anatomic detail can be acquired with conventional structural imaging, but newer …

Radiomics for precision medicine in glioblastoma

K Aftab, FB Aamir, S Mallick, F Mubarak… - Journal of neuro …, 2022 - Springer
Introduction Being the most common primary brain tumor, glioblastoma presents as an
extremely challenging malignancy to treat with dismal outcomes despite treatment. Varying …