Tuberculosis biomarkers discovery: developments, needs, and challenges

RS Wallis, P Kim, S Cole, D Hanna… - The Lancet infectious …, 2013 - thelancet.com
Biomarkers are indispensable to the development of new tuberculosis therapeutics and
vaccines. The most robust biomarkers measure factors that are essential to the underlying …

Diagnostic accuracy of in-house real-time PCR assay for Mycobacterium tuberculosis: a systematic review and meta-analysis

Z Wei, X Zhang, C Wei, L Yao, Y Li, X Zhang… - BMC infectious …, 2019 - Springer
Background In recent years, studies on the diagnostic accuracy of in-house real-time PCR
(hRT-PCR) assay for the detection of Mycobacterium tuberculosis (Mtb) have been reported …

Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta …

EO Babafemi, BP Cherian, L Banting, GA Mills… - Systematic reviews, 2017 - Springer
Background Rapid and accurate diagnosis of tuberculosis (TB) is key to manage the
disease and to control and prevent its transmission. Many established diagnostic methods …

A review approaches to identify enteric bacterial pathogens

J Amani, SA Mirhosseini… - Jundishapur journal of …, 2014 - pmc.ncbi.nlm.nih.gov
Context: Diarrhea is a common disease across the world. According to WHO, every year
about two billion cases of diarrhea are reported in the world. It occurs mainly in the tropical …

Potential for use of the Seegene Anyplex MTB/NTM real-time detection assay in a regional reference laboratory

MD Perry, PL White, M Ruddy - Journal of clinical microbiology, 2014 - Am Soc Microbiol
Requests for direct molecular diagnosis of mycobacterial disease are increasingly
warranted. The Anyplex MTB/NTM assay demonstrates sensitivities, specificities, and …

Utility of Real‐Time Quantitative Polymerase Chain Reaction in Detecting Mycobacterium tuberculosis

Z Lv, M Zhang, H Zhang, X Lu - BioMed research international, 2017 - Wiley Online Library
This study aimed to assess the value of real‐time quantitative polymerase chain reaction
(RT‐qPCR) for the detection of Mycobacterium tuberculosis (MTB). Samples from 192 …

[HTML][HTML] Description, validation, and review of a decade of experience with a laboratory-developed PCR test for detection of Mycobacterium tuberculosis complex in …

SP Buckwalter, BJ Connelly, LK Louison… - Journal of Clinical …, 2022 - Elsevier
Rapid detection of Mycobacterium tuberculosis complex directly from clinical specimens is
critical for patient care. Mycobacterial culture requires days to weeks for results and …

Rapid detection of Mycobacterium tuberculosis based on cyp141 via real-time fluorescence loop-mediated isothermal amplification (cyp141-RealAmp)

Y Zhu, Z Feng, Y Xu, S Luo, R Zhang, X Shi… - Frontiers in Cellular …, 2024 - frontiersin.org
Background The rapid detection of Mycobacterium tuberculosis (MTB) is essential for
controlling tuberculosis. Methods We designed a portable thermocycler-based real-time …

Diagnostic value of combined-diagnostic methods of brain tuberculoma tissue specimens: a case series

B Liang, S Yang, X Zhou, X Ding, J Wang, J Li… - Surgical …, 2024 - liebertpub.com
Background: The diagnosis of brain tuberculoma (BT) is sometimes challenging. Herein, we
presented a case series to evaluate the combined-diagnostic methods, including acid-fast …

Use of a gyrB PCR-RFLP method to diagnose tuberculosis and identify the causative Mycobacterium sp. in cattle and humans

A Oryan, HS Yazdi, S Alidadi… - … and Infectious Diseases, 2022 - Elsevier
GyrB PCR-restriction fragment length polymorphism (RFLP) could be applied to diagnose
bovine and human tuberculosis and detect the causative agent. The lymph nodes and lungs …