Since the early days of the genome era, the scientific community has relied on a single 'reference'genome for each species, which is used as the basis for a wide range of genetic …
The African continent is regarded as the cradle of modern humans and African genomes contain more genetic variation than those from any other continent, yet only a fraction of the …
We conduct high coverage (> 30×) whole-genome sequencing of 180 individuals from 12 indigenous African populations. We identify millions of unreported variants, many predicted …
The deep evolutionary history of African populations, since the emergence of modern humans more than 300,000 years ago, has resulted in high genetic diversity and …
Abstract South Eastern Bantu-speaking (SEB) groups constitute more than 80% of the population in South Africa. Despite clear linguistic and geographic diversity, the genetic …
A pan-African pathogen genomics data sharing platform to support disease outbreaks | Nature Medicine Skip to main content Thank you for visiting nature.com. You are using a browser …
Immunogenomics studies have been largely limited to individuals of European ancestry, restricting the ability to identify variation in human adaptive immune responses across …
In the last three decades, genetic studies have played an increasingly important role in exploring human history. They have helped to conclusively establish that anatomically …
D Twesigomwe, BI Drögemöller… - Clinical …, 2023 - Wiley Online Library
Cytochrome P450 2D6 (CYP2D6) is a key enzyme in drug response owing to its involvement in the metabolism of~ 25% of clinically prescribed medications. The encoding …