Hyperprolactinaemia

I Samperi, K Lithgow, N Karavitaki - Journal of clinical medicine, 2019 - mdpi.com
Hyperprolactinaemia is one of the most common problems in clinical endocrinology. It
relates with various aetiologies (physiological, pharmacological, pathological), the …

Prolactin: A hormone with diverse functions from mammary gland development to cancer metastasis

ÖK Atıcı, N Govindrajan, I Lopetegui-González… - Seminars in Cell & …, 2021 - Elsevier
Prolactin has a rich mechanistic set of actions and signaling in order to elicit developmental
effects in mammals. Historically, prolactin has been appreciated as an endocrine peptide …

[HTML][HTML] Expression of miR-149-3p inhibits proliferation, migration, and invasion of bladder cancer by targeting S100A4

D Yang, G Du, A Xu, X Xi, D Li - American journal of cancer …, 2017 - ncbi.nlm.nih.gov
MicroRNAs play key roles during various crucial cell processes, such as proliferation,
migration, and invasion. In addition, microRNAs have been shown to possess oncogenic …

The relevant participation of prolactin in the genesis and progression of gynecological cancers

A Ramírez-de-Arellano, JC Villegas-Pineda… - Frontiers in …, 2021 - frontiersin.org
Prolactin (PRL) is a hormone produced by the pituitary gland and multiple non-pituitary sites,
vital in several physiological processes such as lactation, pregnancy, cell growth, and …

[HTML][HTML] The Integrated Bioinformatic Approach Reveals the Prognostic Significance of LRP1 Expression in Ovarian Cancer

T Wolde, V Bhardwaj, M Reyad-ul-Ferdous… - International Journal of …, 2024 - mdpi.com
A hyperactive tumour microenvironment (TME) drives unrestricted cancer cell survival, drug
resistance, and metastasis in ovarian carcinoma (OC). However, therapeutic targets within …

[HTML][HTML] Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis

J Zhai, S Li, S Sen, J Vallvé-Juanico, JC Irwin… - Reproductive …, 2022 - Elsevier
Research question Adenomyosis is a common uterine disorder of uncertain causes. Can
transcriptomic analyses of the endometrium and myometrium reveal potential mechanisms …

CORO1C expression is associated with poor survival rates in gastric cancer and promotes metastasis in vitro

X Cheng, X Wang, Z Wu, S Tan, T Zhu… - FEBS Open Bio, 2019 - Wiley Online Library
Coronin‐like actin‐binding protein 1C (CORO1C) is a member of the WD repeat protein
family that regulates actin‐dependent processes by assembling F‐actin. CORO1C was …

A diversity outbred F1 mouse model identifies host-intrinsic genetic regulators of response to immune checkpoint inhibitors

JB Hackett, JE Glassbrook, MC Muñiz, M Bross… - …, 2022 - Taylor & Francis
Immune checkpoint inhibitors (ICI) have improved outcomes for a variety of malignancies;
however, many patients fail to benefit. While tumor-intrinsic mechanisms are likely involved …

GSE1 predicts poor survival outcome in gastric cancer patients by SLC7A5 enhancement of tumor growth and metastasis

K Ding, S Tan, X Huang, X Wang, X Li, R Fan… - Journal of Biological …, 2018 - ASBMB
Gastric cancer remains a malignancy with poor survival outcome. We herein report that
GSE1, a proline-rich protein, possesses a role in the progression of human gastric cancer …

A Novel Small Molecular Antibody, HER2-Nanobody, Inhibits Tumor Proliferation in HER2-Positive Breast Cancer Cells In Vitro and In Vivo

Y Yan, X Cheng, L Li, R Zhang, Y Zhu, Z Wu… - Frontiers in …, 2021 - frontiersin.org
Breast cancer is the most common malignant cancer in women worldwide, especially in
developing countries. Herceptin is a monoclonal antibody with an antitumor effect in HER2 …