Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity
are strongly associated with comorbidities such as hypertension and insulin resistance …

Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors with high prevalence
among adult populations and elevated costs for public health systems worldwide. Despite …

The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Metabolic syndrome (MetS) describes a cluster of cardio-metabolic factors that predispose to
type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular disease (ASCVD). While …

Introduction: Metabolic syndrome represents a cluster of related metabolic abnormalities,
including central obesity, hypertension, dyslipidemia, hyperglycemia, and insulin resistance …

The combination of obesity and hypertension is associated with high morbidity and mortality
because it leads to cardiovascular and kidney disease. Potential mechanisms linking …

Cardiovascular disease is the leading cause of morbidity and mortality in diabetes. Recent
clinical studies indicate that sodium-glucose co-transporter 2 (SGLT2) inhibitors improve …

The primary adrenal cortical steroid hormones, aldosterone, and the glucocorticoids cortisol
and corticosterone, act through the structurally similar mineralocorticoid (MR) and …

Urate is the end-product of the purine metabolism in humans. The dominant source of urate
is endogenous purines and the remainder comes through diet. Approximately two thirds of …

Obesity is an emerging pandemic driven by consumption of a diet rich in fat and highly
refined carbohydrates (a Western diet) and a sedentary lifestyle in both children and adults …