The importance of integrating SNP and cheminformatics resources to pharmacogenomics

HW Chang, LY Chuang, MT Tsai… - Current Drug …, 2012 - ingentaconnect.com
Single nucleotide polymorphisms (SNPs) are the most frequent variants in many genes and
are promising markers in relation to drug responses in pharmacogenomics studies. In this …

[HTML][HTML] SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping

HW Chang, YH Cheng, LY Chuang, CH Yang - BMC bioinformatics, 2010 - Springer
Background PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective
method for SNP genotyping and mutation detection, but the manual mining for restriction …

A novel teaching-learning-based optimization for improved mutagenic primer design in mismatch PCR-RFLP SNP genotyping

YH Cheng - IEEE/ACM Transactions on Computational Biology …, 2015 - ieeexplore.ieee.org
Many single nucleotide polymorphisms (SNPs) for complex genetic diseases are genotyped
by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in …

[HTML][HTML] Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm

CH Yang, YH Cheng, LY Chuang, HW Chang - BMC bioinformatics, 2010 - Springer
Background Polymerase chain reaction with confronting two-pair primers (PCR-CTPP)
method produces allele-specific DNA bands of different lengths by adding four designed …

Towards SDN enabled network control delegation in clouds

MS Malik, M Montanari, JH Huh… - 2013 43rd annual …, 2013 - ieeexplore.ieee.org
In today's IaaS clouds users only get a logical view of the underlying network and have
limited control. Delegating more control to end users would be beneficial but would also …

[HTML][HTML] REHUNT: a reliable and open source package for restriction enzyme hunting

YH Cheng, JJ Liaw, CN Kuo - BMC bioinformatics, 2018 - Springer
Background Restriction enzymes are used frequently in biotechnology. However, manual
mining of restriction enzymes is challenging. Furthermore, integrating available restriction …

Mutagenic primer design for mismatch PCR-RFLP SNP genotyping using a genetic algorithm

CH Yang, YH Cheng, CH Yang… - IEEE/ACM Transactions …, 2012 - ieeexplore.ieee.org
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is useful
in small-scale basic research studies of complex genetic diseases that are associated with …

Associate PCR-RFLP assay design with SNPs based on genetic algorithm in appropriate parameters estimation

LY Chuang, YH Cheng, CH Yang… - IEEE Transactions on …, 2013 - ieeexplore.ieee.org
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is a
commonly used laboratory technique and useful in small-scale basic research studies of …

[PDF][PDF] A natural PCR-RFLP primer design for SNP genotyping using a genetic algorithm

CH Yang, YH Cheng, LY Chuang - … MultiConference of Engineers …, 2010 - researchgate.net
Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) is a
commonly used laboratory technique and useful in small-scale basic research studies of …

PCR-CTPP design for enzyme-free SNP genotyping using memetic algorithm

LY Chuang, YH Cheng, CH Yang - IEEE transactions on …, 2015 - ieeexplore.ieee.org
In recent years, many single nucleotide polymorphisms (SNPs) have been successfully
genotyped by polymerase chain reaction with confronting two-pair primers (PCR-CTPP) …