M Leist, M Jäättelä - Nature reviews Molecular cell biology, 2001 - nature.com
A single family of proteases, the caspases, has long been considered the pivotal executioner of all programmed cell death. However, recent findings of evolutionarily …
JP Nolan, RW Neumar, C Adrie, M Aibiki, RA Berg… - Resuscitation, 2008 - Elsevier
AIM OF THE REVIEW: To review the epidemiology, pathophysiology, treatment and prognostication in relation to the post-cardiac arrest syndrome. METHODS: Relevant articles …
H Nakatomi, T Kuriu, S Okabe, S Yamamoto, O Hatano… - Cell, 2002 - cell.com
The adult brain is extremely vulnerable to various insults. The recent discovery of neural progenitors in adult mammals, however, raises the possibility of repairing damaged tissue …
Matrix metalloproteinases (MMPs) are a gene family of neutral proteases that are important in normal development, wound healing, and a wide variety of pathological processes …
HM Bramlett, WD Dietrich - Journal of Cerebral Blood Flow & …, 2004 - journals.sagepub.com
Current knowledge regarding the pathophysiology of cerebral ischemia and brain trauma indicates that similar mechanisms contribute to loss of cellular integrity and tissue …
G Wassink, ER Gunn, PP Drury, L Bennet… - Frontiers in …, 2014 - frontiersin.org
Acute post-asphyxial encephalopathy occurring around the time of birth remains a major cause of death and disability. The recent seminal insight that allows active neuroprotective …
Connections between neurons are affected within 3 min of stroke onset by massive ischemic depolarization and then delayed cell death. Some connections can recover with prompt …
Apoptosis or programmed cell death has been reported after CNS trauma. However, the significance of this mechanism in the pathophysiology of spinal cord injury, in particular at …
F Adhami, G Liao, YM Morozov, A Schloemer… - The American journal of …, 2006 - Elsevier
Hypoxia is a critical factor for cell death or survival in ischemic stroke, but the pathological consequences of combined ischemia-hypoxia are not fully understood. Here we examine …