Over 500 natural and synthetic amino acids have been genetically encoded in the last two
decades. Incorporating these noncanonical amino acids into proteins enables many …

Our understanding of the complex molecular processes of living organisms at the molecular
level is growing exponentially. This knowledge, together with a powerful arsenal of tools for …

Over the last decade, the ability to genetically encode unnatural amino acids (UAAs) has
evolved rapidly. The programmed incorporation of UAAs into recombinant proteins relies on …

In addition to biochemical gradients and transcriptional networks, cell behavior is regulated
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …

Over the past two decades, genetic code expansion (GCE)-enabled methods for
incorporating noncanonical amino acids (ncAAs) into proteins have significantly advanced …

In a departure from previous top-down or bottom-up strategies used to understand neuronal
circuits, many forward-looking research programs now place the circuit itself at their centre …

Modern light microscopy, including super-resolution techniques, has brought about a
demand for small labeling tags that bring the fluorophore closer to the target. This challenge …

Genetically encoded unnatural amino acids provide powerful strategies for modulating the
molecular functions of proteins in mammalian cells. However, this approach has not been …

Genetic code expansion allows unnatural (non-canonical) amino acid incorporation into
proteins of interest by repurposing the cellular translation machinery. The development of …

Achieving control over cell behavior and pattern formation requires molecular-level
understanding of regulatory mechanisms. Alongside transcriptional networks and …