Plant germline formation: common concepts and developmental flexibility in sexual and asexual reproduction

A Schmidt, MW Schmid, U Grossniklaus - Development, 2015 - journals.biologists.com
The life cycle of flowering plants alternates between two heteromorphic generations: a
diploid sporophytic generation and a haploid gametophytic generation. During the …

The multiple fates of gene duplications: deletion, hypofunctionalization, subfunctionalization, neofunctionalization, dosage balance constraints, and neutral variation

JA Birchler, H Yang - The Plant Cell, 2022 - academic.oup.com
Gene duplications have long been recognized as a contributor to the evolution of genes with
new functions. Multiple copies of genes can result from tandem duplication, from …

A decade of pollen transcriptomics

N Rutley, D Twell - Plant reproduction, 2015 - Springer
Key message Overview of pollen transcriptome studies. Pollen development is driven by
gene expression, and knowledge of the molecular events underlying this process has …

Evolutionarily informed deep learning methods for predicting relative transcript abundance from DNA sequence

JD Washburn, MK Mejia-Guerra… - Proceedings of the …, 2019 - National Acad Sciences
Deep learning methodologies have revolutionized prediction in many fields and show
potential to do the same in molecular biology and genetics. However, applying these …

GPCRomics: GPCR expression in cancer cells and tumors identifies new, potential biomarkers and therapeutic targets

PA Insel, K Sriram, SZ Wiley, A Wilderman… - Frontiers in …, 2018 - frontiersin.org
G protein-coupled receptors (GPCRs), the largest family of targets for approved drugs, are
rarely targeted for cancer treatment, except for certain endocrine and hormone-responsive …

Stable unmethylated DNA demarcates expressed genes and their cis-regulatory space in plant genomes

PA Crisp, AP Marand, JM Noshay… - Proceedings of the …, 2020 - National Acad Sciences
The genomic sequences of crops continue to be produced at a frenetic pace. It remains
challenging to develop complete annotations of functional genes and regulatory elements in …

Zygotic genome activation occurs shortly after fertilization in maize

J Chen, N Strieder, NG Krohn, P Cyprys… - The Plant …, 2017 - academic.oup.com
The formation of a zygote via the fusion of an egg and sperm cell and its subsequent
asymmetric division herald the start of the plant's life cycle. Zygotic genome activation (ZGA) …

Fractionation and subfunctionalization following genome duplications: mechanisms that drive gene content and their consequences

M Freeling, MJ Scanlon, JE Fowler - Current Opinion in Genetics & …, 2015 - Elsevier
A gene's duplication relaxes selection. Loss of duplicate, low-function DNA (fractionation)
sometimes follows, mostly by deletion in plants, but mostly via the pseudogene pathway in …

ZmCCT regulates photoperiod-dependent flowering and response to stresses in maize

H Su, J Liang, SF Abou-Elwafa, H Cheng, D Dou… - BMC plant biology, 2021 - Springer
Background Appropriate flowering time is very important to the success of modern
agriculture. Maize (Zea mays L.) is a major cereal crop, originated in tropical areas, with …

DNA demethylation affects imprinted gene expression in maize endosperm

Q Xu, L Wu, Z Luo, M Zhang, J Lai, L Li, NM Springer… - Genome biology, 2022 - Springer
Background DNA demethylation occurs in many species and is involved in diverse
biological processes. However, the occurrence and role of DNA demethylation in maize …