Schistosomes are parasitic blood flukes, responsible for significant human disease in
tropical and developing nations. Here we review information on the organization of the …

Schistosoma mansoni is the primary causative agent of schistosomiasis, which affects 200
million individuals in 74 countries. We generated 163,000 expressed-sequence tags (ESTs) …

Two distinct families of neuropeptides are known to endow platyhelminth nervous systems–
the FMRFamide-like peptides (FLPs) and the neuropeptide Fs (NPFs). Flatworm FLPs are …

Schistosomiasis (bilharzia) is a tropical disease caused by trematode parasites
(Schistosoma) that affects hundreds of millions of people in the developing world. Currently …

Les plathelminthes, le phylum le plus primitif des métazoaires, occupent une position unique
dans l'évolution du système nerf–muscle. Leur système nerveux consiste essentiellement en …

Serotonin is an important neuroactive substance in all the parasitic helminths. In
Schistosoma mansoni, serotonin is strongly myoexcitatory; it potentiates contraction of the …

Schistosoma mansoni is a well-adapted blood-dwelling parasitic helminth, persisting for
decades in its human host despite being continually exposed to potential immune attack …

Classical schemes of the adult Schistosoma mansoni reproductive system have been
described. In our study, whole adult worms derived from unisexual or mixed infections and …

Muscle tissues are classically divided into two major types, depending on the presence or
absence of striations. In striated muscles, the actin filaments are anchored at Z-lines and the …

One potential physiological target for new antischistosomals is the parasite's system for
excretion of wastes and xenobiotics. P-glycoprotein (Pgp), a member of the ATP-binding …