Recent advances on the antimicrobial activities of Schiff bases and their metal complexes: An updated overview

J Jorge, KF Del Pino Santos, F Timóteo… - Current Medicinal …, 2024 - ingentaconnect.com
Schiff bases represent a valuable class of organic compounds, synthesized via
condensation of primary amines with ketones or aldehydes. They are renowned for …

Urea Hydrogen Peroxide and Ethyl Lactate, an Eco-Friendly Combo System in the Direct C(sp2)–H Bond Selenylation of Imidazo[2,1-b]thiazole and Related …

CAO Moraes, RBC Santos, MFO Cavalcante… - Acs Omega, 2023 - ACS Publications
Herein, we describe a urea hydrogen peroxide-mediated sustainable protocol for the
synthesis of selenylated imidazo [2, 1-b] thiazole by using half molar equivalent diorganyl …

Catalyst- and metal-free C(sp2)–H bond selenylation of (N-hetero)-arenes using diselenides and trichloroisocyanuric acid at room temperature

JSS Neto, IJA Granja, MR Scheide, MS Franco… - Scientific Reports, 2023 - nature.com
In this paper, we report an eco-friendly approach for the C (sp 2)–H bond selenylation of
imidazopyridines and other N-heteroarenes as well as simple arenes at ambient …

KIO4‐mediated Selective Hydroxymethylation/Methylenation of Imidazo‐Heteroarenes: A Greener Approach

MS Franco, S Saba, J Rafique… - Angewandte Chemie …, 2021 - Wiley Online Library
Herein, we report a KIO4‐mediated, sustainable and chemoselective approach for the one‐
pot C (sp2)− H bond hydroxymethylation or methylenation of imidazo‐heteroarenes with …

IP‐Se‐06, a Selenylated Imidazo[1,2‐a]pyridine, Modulates Intracellular Redox State and Causes Akt/mTOR/HIF‐1α and MAPK Signaling Inhibition, Promoting …

DC Dos Santos, J Rafique, S Saba… - Oxidative Medicine …, 2022 - Wiley Online Library
Glioblastoma multiforme (GBM) is a notably lethal brain tumor associated with high
proliferation rate and therapeutic resistance, while currently effective treatment options are …

Versatile Electrochemical Synthesis of Selenylbenzo[b]Furan Derivatives Through the Cyclization of 2-Alkynylphenols

CV Doerner, MR Scheide, CR Nicoleti… - Frontiers in …, 2022 - frontiersin.org
We report an electrochemical oxidative intramolecular cyclization reaction between 2-
alkynylphenol derivatives and different diselenides species to generate a wide variety of …

Synthesis of 3-selanyl-isoflavones from 2-hydroxyphenyl enaminones using trichloroisocyanuric acid (TCCA): a sustainable approach

CV Doerner, JSS Neto, CR Cabreira, S Saba… - New Journal of …, 2023 - pubs.rsc.org
We hereby present an original and sustainable synthetic methodology for the synthesis of 3-
selanyl-isoflavones from 2-hydroxyphenyl enaminones and diorganoyl diselenides. The …

Selenylated Imidazo [1,2-a]pyridine Induces Apoptosis and Oxidative Stress in 2D and 3D Models of Colon Cancer Cells

GB Gomes, CS Zubieta, JS Guilhermi, MC Toffoli-Kadri… - Pharmaceuticals, 2023 - mdpi.com
Colon cancer incidence rates are increasing annually, a scenario aggravated by genetic
and epigenetic alterations that promote drug resistance. Recent studies showed that novel …

Oxidative Stress and Chronic Myeloid Leukemia: A Balance between ROS-Mediated Pro-and Anti-Apoptotic Effects of Tyrosine Kinase Inhibitors

A Allegra, G Mirabile, S Caserta, F Stagno, S Russo… - Antioxidants, 2024 - mdpi.com
The balanced reciprocal translocation t (9; 22)(q34; q11) and the BCR-ABL fusion gene,
which produce p210 bcr-abl protein production with high tyrosine kinase activity, are …

Catalytic antioxidant activity of bis-aniline-derived diselenides as GPx mimics

GV Botteselle, WC Elias, L Bettanin, RFS Canto… - Molecules, 2021 - mdpi.com
Herein, we describe a simple and efficient route to access aniline-derived diselenides and
evaluate their antioxidant/GPx-mimetic properties. The diselenides were obtained in good …