Glioblastoma (GBM) continues to be the most aggressive cancer of the brain. The dismal
prognosis is largely attributed to the microenvironment surrounding tumor cells. Astrocytes …

Malignant gliomas are aggressive brain tumors with limited therapeutic options, possibly
because of highly tumorigenic subpopulations of glioma stem cells. These cells require …

The main characteristic of glioma is recurrence, even after intensive multidisciplinary
treatment. Studies show that enhanced invasive ability will increase the ability of tumor cells …

Cancer is the leading cause of death worldwide; thus, it is necessary to find successful
strategies. Several growth factors, such as vascular endothelial growth factor (VEGF), basic …

Culturing cells and tissues in vitro has provided valuable insights into the molecular
mechanisms regulating redox signaling in cells with implications for medicine. However …

Glioblastomas (GBM) are lethal brain tumors where poor outcome is attributed to cellular
heterogeneity, therapeutic resistance, and a highly infiltrative nature. These characteristics …

Background Glioblastoma multiforme (GBM) is a rapidly growing malignant brain tumor,
which has been reported to be organized in a hierarchical fashion with cancer stem cells …

Surgery is the first line therapy for glioma. However, glioma recurs in 90% of the patients in
the resection margin. The impact of surgical brain injury (SBI) on glioma recurrence is …

Aim: The aim of the present study was to investigate the efficacy of the traditional Chinese
medicine (TCM), astragaloside IV (AS-IV) and curcumin on tumor growth and angiogenesis …

Interferon-induced transmembrane protein 3 (IFITM3) has been previously verified to be an
endosomal protein that prevents viral infection. Recent findings suggested IFITM3 as a key …