Despite having a wide range of therapeutic advantages, glycyrrhizin (GL) has few
commercial applications due to its poor aqueous solubility. In this study, we combined the …

The study aimed to prepare inclusion complexes of 1, 3-diphenylurea (DPU) with β-
cyclodextrin (βCD) and 2-hydroxypropyl-β-cyclodextrin (HP-βCD) using a three-dimensional …

Ursolic acid (UA), a pentacyclic triterpenoid, possesses a variety of biochemical activities,
including alpha-glucosidase inhibitory activity, but its poor solubility has limited its clinical …

Hydroxypropyl-β-cyclodextrin (HPβCD) is a derivatized cyclodextrin in which several H
atoms on the hydroxyls of the glucose rings are substituted by 2-hydroxypropyl groups. The …

We study how the size of the macrocycle of native cyclodextrins and their hydration influence
the inclusion of ritonavir under mechanical grinding conditions. A procedure is proposed to …

The compound Perillaldehyde (PA) is a bioactive constituent found in natural Perilla oil,
exhibiting remarkable antibacterial and antioxidant activity. However, the instability of this …

Context Hydroxypropyl-β-cyclodextrin (HPβCD) is one of the derivatized cyclodextrins most
widely used as an excipient in the pharmaceutical industry, for its capacity to improve certain …

Изучено влияние размера макроцикла нативных циклодекстринов и их гидратации на
инкапсуляцию ритонавира в условиях механического перемалывания. Разработан …