Allergic rhinitis is clinically defined as a symptomatic disorder of the nose induced by an IgE-
mediated inflammation after allergen exposure of the membranes lining the nose. Symptoms …

Asthma is a chronic disease of the airways that has long been viewed predominately as an
inflammatory condition. Accordingly, current therapeutic interventions focus primarily on …

Using a compound microscope and the blood of several animals (including the elephant!),
the English anatomist, TW Jones, discovered, in 1846, that some white blood cells contained …

A chronic inflammatory process is almost invariably associated with tissue damage and
healing. Healing results in repair and replacement of dead or damaged cells by viable cells …

Publisher Summary The chapter reviews recent findings on the biology of the eosinophil,
particularly distinctive eosinophil features, and discusses the possible role of the eosinophil …

▪ Abstract Leukotrienes (LTs) are the ultimate synthetic product resulting from the
intracellular hydrolysis of membrane phospholipid at the nuclear envelope in inflammatory …

Vernal keratoconjunctivitis (VKC) is a severe type of allergic conjunctival disease
characterized by the presence both of various corneal epithelial and stromal lesions as well …

Background: Such CC chemokines as eotaxin and RANTES induce preferential eosinophil
recruitment in allergic inflammation. They also elicit proinflammatory effector functions of …

Eosinophils are blood and tissue immune cells that participate in a diverse range of activities
normally beneficial for the host defense, but in circumstances of untoward inflammatory …

Eosinophils play a protective role in host immunity to infections by parasitic worms and,
detrimentally, are involved in the pathophysiology of asthma and other allergic diseases …