Human papillomaviruses (HPVs) are small double‐stranded circular DNA viruses with 8 kb
genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have …

Studies of the mechanistic (mammalian) target of rapamycin inhibitors (mTOR) represent a
step towards the targeted treatment of gynecological cancers. It has been shown that women …

Head and neck squamous cell carcinomas (SCCHN) arise in the mucosa of the upper
aerodigestive tract at multiple anatomic sites. While tobacco and alcohol exposure remain …

The high‐risk human papillomavirus E6 proteins have been shown to interact with and lead
to degradation of PDZ‐domain‐containing proteins through its carboxy‐terminal motif. This …

In light of the development of RAS inhibitors, a reliable assessment of the prevalence of RAS
mutations and their correlation with the clinical features of patients with HNC is crucially …

Our previous studies revealed that manganese superoxide dismutase (SOD2) contributes to
the migration and invasion of tongue squamous cell carcinoma (TSCC). The purpose of the …

Human papillomavirus (HPV) infections are the primary drivers of cervical cancers, and often
HPV DNA gets integrated into the host genome. Although the oncogenic impact of HPV …

Malignant transformation involves an orchestrated rearrangement of cell cycle regulation
mechanisms that must balance autonomic mitogenic impulses and deleterious oncogenic …

Abstract General control nondepressible 5 (GCN5), the first identified transcription‐related
lysine acetyltransferase (KAT), is an important catalytic component of a transcriptional …

Oncogenic mutations of RAS genes, found in about 30% of human cancers, are considered
to play important roles in cancer development. However, oncogenic RAS can also induce …