The determination of endogenous substances is of great significance for obtaining important
biotic information such as biological components, metabolic pathways and disease …

This review presents, from a critical perspective, the most remarkable and recent
applications of solid-phase microextraction (SPME) as a sample preparation tool for mass …

Despite the importance of monitoring and correlating neurotransmitter concentrations in the
brain with observable behavior and brain areas in which they act, in vivo measurement of …

The introduction of matrix compatible solid phase microextraction (SPME) coatings in recent
years has enabled analysis of complex matrices by direct immersion, and thus has …

Lipidomics is a rapidly growing field, fueled by developments in analytical instrumentation
and bioinformatics. To date, most researchers and industries have employed their own …

Growing threats in modern medicine, eg, antibiotic resistance, along with urgent need for
rapid diagnostic techniques and introduction of new drugs, induced intensive clinical and …

Extraction of endogenous compounds and drugs and their corresponding metabolites from
complex matrices, such as biofluids and solid tissues, requires adequate analytical …

Introduction Several software packages containing diverse algorithms are available for
processing Liquid Chromatography-Mass Spectrometry (LC–MS) chromatographic data and …

Solid phase microextraction (SPME) is one of the most popular sample preparation methods
which can be applied to organic compounds allowing the simultaneous extraction and pre …

This work presents an evaluation of solid-phase microextraction (SPME) SPME in
combination with liquid chromatography-high resolution mass spectrometry (LC-HRMS) as …