Optical coherence elastography–OCT at work in tissue biomechanics

KV Larin, DD Sampson - Biomedical optics express, 2017 - opg.optica.org
Optical coherence elastography (OCE), as the use of OCT to perform elastography has
come to be known, began in 1998, around ten years after the rest of the field of elastography …

Strain and elasticity imaging in compression optical coherence elastography: the two‐decade perspective and recent advances

VY Zaitsev, AL Matveyev, LA Matveev… - Journal of …, 2021 - Wiley Online Library
Quantitative mapping of deformation and elasticity in optical coherence tomography has
attracted much attention of researchers during the last two decades. However, despite …

Optical coherence elastography in ophthalmology

MA Kirby, I Pelivanov, S Song… - … of biomedical optics, 2017 - spiedigitallibrary.org
Optical coherence elastography (OCE) can provide clinically valuable information based on
local measurements of tissue stiffness. Improved light sources and scanning methods in …

Histological validation of in vivo assessment of cancer tissue inhomogeneity and automated morphological segmentation enabled by Optical Coherence Elastography

AA Plekhanov, MA Sirotkina, AA Sovetsky… - Scientific reports, 2020 - nature.com
We present a non-invasive (albeit contact) method based on Optical Coherence
Elastography (OCE) enabling the in vivo segmentation of morphological tissue constituents …

Vector method for strain estimation in phase-sensitive optical coherence elastography

AL Matveyev, LA Matveev, AA Sovetsky… - Laser Physics …, 2018 - iopscience.iop.org
A noise-tolerant approach to strain estimation in phase-sensitive optical coherence
elastography, robust to decorrelation distortions, is discussed. The method is based on …

OCT-elastography-based optical biopsy for breast cancer delineation and express assessment of morphological/molecular subtypes

EV Gubarkova, AA Sovetsky, VY Zaitsev… - Biomedical optics …, 2019 - opg.optica.org
Application of compressional optical coherence elastography (OCE) for delineation of tumor
and peri-tumoral tissue with simultaneous assessment of morphological/molecular subtypes …

Optimized phase gradient measurements and phase-amplitude interplay in optical coherence elastography

VY Zaitsev, AL Matveyev, LA Matveev… - Journal of …, 2016 - spiedigitallibrary.org
In compressional optical coherence elastography, phase-variation gradients are used for
estimating quasistatic strains created in tissue. Using reference and deformed optical …

Wide-field optical coherence micro-elastography for intraoperative assessment of human breast cancer margins

WM Allen, L Chin, P Wijesinghe, RW Kirk… - Biomedical optics …, 2016 - opg.optica.org
Incomplete excision of malignant tissue is a major issue in breast-conserving surgery, with
typically 20-30% of cases requiring a second surgical procedure arising from postoperative …

Manually-operated compressional optical coherence elastography with effective aperiodic averaging: demonstrations for corneal and cartilaginous tissues

AA Sovetsky, AL Matveyev, LA Matveev… - Laser Physics …, 2018 - iopscience.iop.org
Compressional elastography in optical coherence tomography (OCT) is based on relating
the sought spatial distribution of stiffness with initially reconstructed strain distribution by …

Practical obstacles and their mitigation strategies in compressional optical coherence elastography of biological tissues

VY Zaitsev, AL Matveyev, LA Matveev… - Journal of Innovative …, 2017 - World Scientific
In this paper, we point out some practical obstacles arising in realization of compressional
optical coherence elastography (OCE) that have not attracted sufficient attention previously …