Radiation damage inflicted during diffraction data collection in macromolecular
crystallography has re-emerged in the last decade as a major experimental and …

The genome of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
coronavirus has a capping modification at the 5′-untranslated region (UTR) to prevent its …

In this review, recent progress in understanding the direct effects of radiation on the structure
and stability of collagen, the most abundant protein in the human body, and other proteins is …

The most important mode of bacterial resistance to β-lactam antibiotics is the expression of β-
lactamases. New cyclobutanone analogues of penams and penems have been prepared …

Bacteriorhodopsin (bR) provides light-driven vectorial proton transport across a cell
membrane. Creation of electrochemical potential at the membrane is a universal step in …

X-rays, electrons, and neutrons probe different properties of matter. X-rays feel electron
density (ED). Electrons sense the electrostatic potential (ESP) of electrons and nuclei …

Abstract Aldose reductase 2 (ALR2), which catalyzes the reduction of glucose to sorbitol
using NADP as a cofactor, has been implicated in the etiology of secondary complications of …

A prototype of a 96-well plate scanner for in situ data collection has been developed at the
Structural Biology Center (SBC) beamline 19-ID, located at the Advanced Photon Source …

The temperature-dependence of radiation damage in macromolecular X-ray crystallography
is currently much debated. Most protein crystallographic studies are based on data collected …

Overall and site-specific X-ray-induced damage to porcine pancreatic elastase was studied
at atomic resolution at temperatures of 100 and 15 K. The experiments confirmed that …