Long noncoding RNAs biomarker‐based cancer assessment

M Sarfi, M Abbastabar, E Khalili - Journal of cellular physiology, 2019 - Wiley Online Library
Cancer diagnosis have mainly relied on the incorporation of molecular biomarkers as part of
routine diagnostic tool. The molecular alteration ranges from those involving DNA, RNA …

The clinical utility of lncRNAs and their application as molecular biomarkers in breast cancer

C Arriaga-Canon, L Contreras-Espinosa… - International journal of …, 2023 - mdpi.com
Given their tumor-specific and stage-specific gene expression, long non-coding RNAs
(lncRNAs) have demonstrated to be potential molecular biomarkers for diagnosis …

A review of cancer genetics and genomics studies in Africa

SO Rotimi, OA Rotimi, B Salhia - Frontiers in oncology, 2021 - frontiersin.org
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

LncRNA H19 promotes epithelial mesenchymal transition and metastasis of esophageal cancer via STAT3/EZH2 axis

MJ Chen, J Deng, C Chen, W Hu, YC Yuan… - The international journal …, 2019 - Elsevier
Background Long non-coding RNA H19 (lncRNA H19) has been widely reported in
esophageal cancer (EC), and previous study had found that lncRNAH19 was up-regulated …

Multiple function of lncRNA MALAT1 in cancer occurrence and progression

F Malakoti, N Targhazeh, H Karimzadeh… - Chemical biology & …, 2023 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) have received particular attention in the last decade due
to its engaging in carcinogenesis and tumorigenesis. Metastasis‐associated lung …

MALAT1miR663a negative feedback loop in colon cancer cell functions through direct miRNA–lncRNA binding

W Tian, Y Du, Y Ma, L Gu, J Zhou, D Deng - Cell death & disease, 2018 - nature.com
The lncRNA MALAT1 has multiple biological functions, including influencing RNA
processing, miRNA sponging, and cancer development. It is acknowledged that miR663a …

Application value of circulating LncRNA in diagnosis, treatment, and prognosis of breast cancer

M Li, Y Zhao, H Li, X Deng, M Sheng - Functional & Integrative Genomics, 2023 - Springer
Breast cancer is the malignant tumor with the highest incidence in women worldwide. It is
highly heterogeneous, has a high incidence of drug resistance, recurrence, and metastasis …

Novel Insights Into MALAT1 Function as a MicroRNA Sponge in NSCLC

Q Zhou, L Liu, J Zhou, Y Chen, D Xie, Y Yao… - Frontiers in …, 2021 - frontiersin.org
The long non-coding RNA metastasis-associated lung adenocarcinoma transcript-1
(MALAT1) was initially found to be overexpressed in early non-small cell lung cancer …

Coding roles of long non-coding RNAs in breast cancer: Emerging molecular diagnostic biomarkers and potential therapeutic targets with special reference to …

D Kashyap, R Sharma, N Goel, HS Buttar… - Frontiers in …, 2023 - frontiersin.org
Dysregulation of epigenetic mechanisms have been depicted in several pathological
consequence such as cancer. Different modes of epigenetic regulation (DNA methylation …

Genomics in Egypt: current status and future aspects

EA El-Attar, RM Helmy Elkaffas, SA Aglan… - Frontiers in …, 2022 - frontiersin.org
Egypt is the third most densely inhabited African country. Due to the economic burden and
healthcare costs of overpopulation, genomic and genetic testing is a huge challenge …